Research Scientists

Latest publications

• The effects of trifluoperazine on brain edema, aquaporin-4 expression and metabolic markers during the acute phase of stroke using photothrombotic mouse model

  Journal article

  Sylvain NJ. et al, (2021), Biochimica et Biophysica Acta - Biomembranes, 1863

• Revisiting dopamine-acetylcholine imbalance in Parkinson’s disease: glutamate co-transmission as an exciting partner in crime

  Journal article

  CRAGG S. and Zhang Y-F., (2021), Neuron

• Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling.

  Journal article

  Munshaw S. et al, (2021), J Clin Invest

• Striatal dopamine transporter function is facilitated by converging biology of α-synuclein and cholesterol

  Journal article

  BRIMBLECOMBE K. et al, (2021), Frontiers in Cellular Neuroscience

• Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice

  Journal article

  Sachse G. et al, (2021), Wellcome Open Research, 5, 15 - 15

• Characterization of a common progenitor pool of the epicardium and myocardium.

  Journal article

  Tyser RCV. et al, (2021), Science, 371

• Hyperpolarized 13 C magnetic resonance imaging for noninvasive assessment of tissue inflammation.

  Journal article

  Anderson S. et al, (2021), NMR Biomed, 34

• Analysis of epicardial genes in embryonic mouse hearts with flow cytometry

  Journal article

  REDPATH A. et al, (2021), STAR Protocols, 2

• High-Throughput Screening Platforms in the Discovery of Novel Drugs for Neurodegenerative Diseases.

  Journal article

  Aldewachi H. et al, (2021), Bioengineering (Basel), 8

• The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion.

  Journal article

  Sachse G. et al, (2021), Diabetes

• REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model.

  Journal article

  Ryan BJ. et al, (2021), J Neurosci

• Functional analysis of a gene-edited mouse to gain insights into the disease mechanisms of a titin missense variant

  Journal article

  JIANG H. et al, (2021), Basic Research in Cardiology

• Rapid, B 1 -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.

  Journal article

  Miller JJ. et al, (2021), Magn Reson Med

• Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart.

  Journal article

  Cahill TJ. et al, (2021), Development, 148

• Proof-of-Principle Demonstration of Direct Metabolic Imaging Following Myocardial Infarction Using Hyperpolarized 13C CMR.

  Journal article

  Apps A. et al, (2021), JACC Cardiovasc Imaging

• Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.

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  Simon JN. et al, (2021), Circulation, 143, 449 - 465

• A 3D hybrid-shot spiral sequence for hyperpolarized 13 C imaging.

  Journal article

  Tyler A. et al, (2021), Magn Reson Med, 85, 790 - 801

• Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer's disease.

  Journal article

  Bengoa-Vergniory N. et al, (2021), Acta Neuropathol Commun, 9

• A dynamic model of the body gas stores for carbon dioxide, oxygen and inert gases that incorporates circulatory transport delays to and from the lung.

  Journal article

  Magor-Elliott SRM. et al, (2021), J Appl Physiol (1985)

• Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.

  Journal article

  Savic D. et al, (2021), NMR Biomed