Sleep, brain and behaviour laboratory
Sleep is a basic physiological state of the organism occupying approximately one third of our lives, yet little is known about its specific functions. We do know, however, that extending wakefulness for just a few hours beyond a habitual bedtime leads to attention lapses, inability to concentrate, memory impairments and many other cognitive deficits. Why is sleep necessary? This question is of paramount importance, since insufficient or poor sleep is experienced by millions of people in the modern society, it is typical for many neurodegenerative, psychiatric, respiratory and other diseases, and is a frequent complaint in the elderly. However, lack of understanding of neurophysiologic mechanisms underlying the link between sleep need and cognition and a paucity of suitable experimental animal models directly translatable to humans, hampers our progress in the development of therapeutic interventions for sleep improvement.
In our research we use a broad range of techniques and approaches, such as behavioural tasks, electrophysiology, transgenic mouse models, local brain microstimulation and pharmacology.