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Luana Campos Soares
Postdoctoral Research Scientist
RESEARCH INTERESTS
My research interest resides in the understanding molecular cues within cortical brain development and how they can be used to treat brain injury and damage.
I am currently working on The Oxford Martin Programme on 3D Printing for Brain Repair, which will advance our knowledge on basic neurosciences with added potential advances for translational medicine. The project has three main goals, all equally puzzling. Firstly, we intend to deepen our understanding of human pluripotent stem cells (hPSCs) neuronal differentiation process, as the ability to generate neurons from different cortical layers is an essential aspect of our approach. Second, we will pre-organize these neurons in layers and columns using the 3D printing technology. Finally, we will test the ability of these constructs to integrate in the existing nervous tissue in vivo.
Additionally, I continue to work with early neural stem cell commitment and polarity, focusing on the role of Galectin-3 in this process. Galectin-3 is a lectin strongly expressed in the stem cells niche in the brain; however, its specific functions remain to be elucidated.
BIOGRAPHY
I have completed DPhil degree at the University of Oxford in 2021. I worked in a collaborative project between Francis Szele and Eric O'Neill groups.
Before coming to Oxford, I graduated in Biology at the Universidade Estadual Paulista and completed a Master's degree in the A.C.Camargo Cancer Center in Brazil.
Recent publications
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Journal article
Jin Y. et al, (2023), Nat Commun, 14
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Journal article
Soares LC. et al, (2021), Cells, 10
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Journal article
Al-Dalahmah O. et al, (2020), Stem Cells, 38, 1149 - 1158
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Journal article
Al-Dalahmah O. et al, (2020), Glia, 68, 435 - 450