Centre for Cellular and Molecular Neurobiology
The Centre for Cellular and Molecular Neurobiology (formerly the Oxford Centre for Gene Function) is a multidisciplinary international centre for research into the biology of neuronal and brain function and structures at the cellular and subcellular level. It is dedicated to the study of cells of the nervous system and the organisation of these cells into functional circuits that process information and mediate behaviour. Researchers also aim to elucidate the disease mechanisms underlying disorders of the nervous system.
Since its original conception as the OCGF in 2000, the centre has shed light on gene function from basic science through to the clinic. Understanding gene function is the key to understanding disease. Successful mapping of the human genome enables researchers to determine the function of all the genes in the human genome and to explain how defects in their sequence give rise to disease. The Centre's science has been aimed at the prevention and treatment of diseases such as dementia, Duchenne muscular dystrophy and diabetes, bringing together leading scientists across genetics and physiology to provide an integrated approach to facilitating the discovery and development of novel targets for therapeutic intervention.