Andreas Koschinski

• Unique regulation of cAMP signals at distinct excitation-contraction coupling (EEC) regulatory sites in adult cardiac myocytes

  Surdo NC. et al, (2015), EUROPEAN HEART JOURNAL, 36, 370 - 371

• Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells.

  Parnell E. et al, (2015), Biochim Biophys Acta, 1853, 1749 - 1758

• A novel approach combining real-time imaging and the patch-clamp technique to calibrate FRET-based reporters for cAMP in their cellular microenvironment.

  Koschinski A. and Zaccolo M., (2015), Methods Mol Biol, 1294, 25 - 40

• Analysis of compartmentalized cAMP: a method to compare signals from differently targeted FRET reporters.

  Stangherlin A. et al, (2014), Methods Mol Biol, 1071, 59 - 71

• Analysis of compartmentalized cAMP: A method to compare signals from differently targeted FRET reporters

  Stangherlin A. et al, (2014), Methods in Molecular Biology, 1071, 59 - 71

• PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome.

  Terrin A. et al, (2012), J Cell Biol, 198, 607 - 621

• Hypersusceptibility of neutrophil granulocytes towards lethal action of free fatty acids contained in enzyme-modified atherogenic low density lipoprotein.

  Lux CA. et al, (2009), Atherosclerosis, 207, 116 - 122

• RNase-induced apoptosis: fate of calcium-activated potassium channels.

  Ilinskaya ON. et al, (2008), Biochimie, 90, 717 - 725

• A short treatment of cells with the lanthanide ions La3+, Ce3+, Pr3+ or Nd3+ changes the cellular chemistry into a state in which RNA replication of flaviviruses is specifically blocked without interference with host-cell multiplication.

  Wengler G. et al, (2007), J Gen Virol, 88, 3018 - 3026

• Autocatalytic cleavage of Clostridium difficile toxin B.

  Reineke J. et al, (2007), Nature, 446, 415 - 419

• Why Escherichia coli alpha-hemolysin induces calcium oscillations in mammalian cells--the pore is on its own.

  Koschinski A. et al, (2006), FASEB J, 20, 973 - 975

• Why Escherichia coli α-hemolysin induces calcium oscillations in mammalian cells - The pore is on its own

  Koschinski A. et al, (2006), FASEB Journal, 20

• Rare earth ions block the ion pores generated by the class II fusion proteins of alphaviruses and allow analysis of the biological functions of these pores.

  Koschinski A. et al, (2005), J Gen Virol, 86, 3311 - 3320

• Functional transfer of eukaryotic expression plasmids to mammalian cells by Listeria monocytogenes: a mechanistic approach.

  Zelmer A. et al, (2005), J Gene Med, 7, 1097 - 1112

• During entry of alphaviruses, the E1 glycoprotein molecules probably form two separate populations that generate either a fusion pore or ion-permeable pores.

  Wengler G. et al, (2004), J Gen Virol, 85, 1695 - 1701

• Cytotoxicity of RNases is increased by cationization and counteracted by K(Ca) channels.

  Ilinskaya ON. et al, (2004), Biochem Biophys Res Commun, 314, 550 - 554

• The membrane proteins of flaviviruses form ion-permeable pores in the target membrane after fusion: identification of the pores and analysis of their possible role in virus infection.

  Koschinski A. et al, (2003), J Gen Virol, 84, 1711 - 1721

• Entry of alphaviruses at the plasma membrane converts the viral surface proteins into an ion-permeable pore that can be detected by electrophysiological analyses of whole-cell membrane currents.

  Wengler G. et al, (2003), J Gen Virol, 84, 173 - 181

• Listeriolysin of Listeria monocytogenes forms Ca2+-permeable pores leading to intracellular Ca2+ oscillations.

  Repp H. et al, (2002), Cell Microbiol, 4, 483 - 491

• Lysophospholipids induce membrane hyperpolarization in microglia by activation of IKCa1 Ca(2+)-dependent K(+) channels.

  Schilling T. et al, (2002), Neuroscience, 109, 827 - 835

• Activation of a Ca2+-dependent K+ current in mouse fibroblasts by sphingosine-1-phosphate involves the protein tyrosine kinase c-Src.

  Repp H. et al, (2001), Naunyn Schmiedebergs Arch Pharmacol, 363, 295 - 301

• Bacillus intermedius ribonuclease as inhibitor of cell proliferation and membrane current.

  Ilinskaya O. et al, (2001), Toxicology, 156, 101 - 107

Recent Publications

• Unique regulation of cAMP signals at distinct excitation-contraction coupling (EEC) regulatory sites in adult cardiac myocytes

  Surdo NC. et al, (2015), EUROPEAN HEART JOURNAL, 36, 370 - 371

• Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells.

  Parnell E. et al, (2015), Biochim Biophys Acta, 1853, 1749 - 1758

• A novel approach combining real-time imaging and the patch-clamp technique to calibrate FRET-based reporters for cAMP in their cellular microenvironment.

  Koschinski A. and Zaccolo M., (2015), Methods Mol Biol, 1294, 25 - 40

• Analysis of compartmentalized cAMP: a method to compare signals from differently targeted FRET reporters.

  Stangherlin A. et al, (2014), Methods Mol Biol, 1071, 59 - 71

• Analysis of compartmentalized cAMP: A method to compare signals from differently targeted FRET reporters

  Stangherlin A. et al, (2014), Methods in Molecular Biology, 1071, 59 - 71