Thomas Nicol
Postdoctoral Research Scientist
My work focuses on the role of Calhm2 in the metabolism of the heart. By investigating the role of Calhm2 in the metabolic switching of mitochondria in the post natal heart I aim to uncover how it is involved in cardiomyocyte differentiation and how defects in this process can lead to congenital heart defects.
Recent publications
FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes.
Journal article
Dennis KMJH. et al, (2025), Circ Res, 136, 1545 - 1560
Tissue-specific differences in the assembly of mitochondrial Complex I are revealed by a novel ENU mutation in ECSIT.
Journal article
Nicol T. et al, (2023), Cardiovasc Res, 119, 2213 - 2229
Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.
Journal article
Chu SM. et al, (2023), Exp Physiol, 108, 874 - 890
Chronically elevated branched chain amino acid levels are pro-arrhythmic.
Journal article
Portero V. et al, (2022), Cardiovasc Res, 118, 1742 - 1757
Isolation and In vitro Culture of Bone Marrow-Derived Macrophages for the Study of NO-Redox Biology.
Journal article
Diotallevi M. et al, (2022), J Vis Exp

