Researcher Society

About Us

Run by and for researchers, The DPAG Researcher Society aims to promote interactions between postdocs, research assistants and other research scientists to create a friendly network of skills and expertise and to welcome new researchers to the Department.

All researchers will be added automatically to a mailing list when they start to be kept up to date with events etc.

Committee

Stefania Monterisi, Chair

Susann Bruche, Vice-Chair

Luana Campos Soares

Claudio Cortes Rodriguez, DPAG Research Staff Representative

Johanna Michl

Christophe Ravaud

Ozren Stojanovic

Nikita Ved, Outreach Representative and Social Media Manager

Researcher News

DPAG researchers showcased at premier European Society of Cardiology meeting

5 May 2022

DPAG scientists across four research groups were highlighted at the major annual European Society of Cardiology basic science conference (FCVB 2022). Congratulations are in order for Dr KC Park on receiving the Young Investigator Award and to Dr Elisabetta Gamen on winning the Moderated Poster Prize.

DPAG Postdoctoral Researcher acknowledged for developmental and cell biology research

19 April 2022

Dr Matthew Stower was selected to give an oral presentation of his work and his abstract won the second prize at the Joint Spring Meeting of the British Society for Developmental Biology (BSDB) and the British Society for Cell Biology (BSCB).

Map of nuclear and cytoplasmic pH recorded in neonatal cardiac cells incubated in various medium pH: 6.24, 6.49, 6.80. 6.98, 7.10 and 7.45. This is colour coded on a scale from 6.1 - 7.6 pH.

The effect of nuclear pH on cardiac gene expression

13 April 2022

Research led by Dr Alzbeta Hulikova and Professor Pawel Swietach has, for the first time, described the potential regulation of nuclear acid-base chemistry in neonatal and adult cardiomyocytes, and explained its relevance in the context of heart physiology and pathology.

Side by side pancreatic islets demonstrating prevalence of glucagon in normal animals and heavily reduced glucagon when ACC1 is knocked out.

New insights into little understood regulator of blood sugar levels

25 March 2022

A new Novo Nordisk project paper has uncovered the role of ACC1 enzyme in the regulation of glucagon secretion for the first time. This raises the prospect of a potential new therapeutic target in the context of type 2 diabetes and metabolic disorders characterised by hyperglycaemia.

Cy5.5-conjugated pH-(low)-insertion peptide (pHLIP, red) to label acidic tumour regions and Hoechst-33342 (blue) to label cell nuclei in the fresh frozen tumor sections of wild-type SW1222 xenografts.

New gene target identified to prevent tumour growth under acidity

11 March 2022

A new paper led by Dr Johanna Michl and Professor Pawel Swietach from DPAG’s Swietach Group has identified a new gene that allows cancer cells to survive in the typically acidic microenvironment of a malignant tumour. They have discovered drugs that inhibit the gene in other medical conditions also selectively kill cancer cells at acidic pH, without damaging healthy tissue. This defines a novel strategy for targeting acidic tumour regions.

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