Researcher Society
About Us
Run by and for researchers, The DPAG Researcher Society aims to promote interactions between postdocs, research assistants and other research scientists to create a friendly network of skills and expertise and to welcome new researchers to the Department.
All researchers will be added automatically to a mailing list when they start to be kept up to date with events etc.
Committee
Stefania Monterisi, Chair
Susann Bruche, Vice-Chair
Claudio Cortes Rodriguez, DPAG Research Staff Representative
Nikita Ved, Outreach Representative and Social Media Manager
Researcher News
DPAG researchers showcased at premier European Society of Cardiology meeting
5 May 2022
DPAG scientists across four research groups were highlighted at the major annual European Society of Cardiology basic science conference (FCVB 2022). Congratulations are in order for Dr KC Park on receiving the Young Investigator Award and to Dr Elisabetta Gamen on winning the Moderated Poster Prize.
DPAG Postdoctoral Researcher acknowledged for developmental and cell biology research
19 April 2022
Dr Matthew Stower was selected to give an oral presentation of his work and his abstract won the second prize at the Joint Spring Meeting of the British Society for Developmental Biology (BSDB) and the British Society for Cell Biology (BSCB).
The effect of nuclear pH on cardiac gene expression
13 April 2022
Research led by Dr Alzbeta Hulikova and Professor Pawel Swietach has, for the first time, described the potential regulation of nuclear acid-base chemistry in neonatal and adult cardiomyocytes, and explained its relevance in the context of heart physiology and pathology.
New insights into little understood regulator of blood sugar levels
25 March 2022
A new Novo Nordisk project paper has uncovered the role of ACC1 enzyme in the regulation of glucagon secretion for the first time. This raises the prospect of a potential new therapeutic target in the context of type 2 diabetes and metabolic disorders characterised by hyperglycaemia.
New gene target identified to prevent tumour growth under acidity
11 March 2022
A new paper led by Dr Johanna Michl and Professor Pawel Swietach from DPAG’s Swietach Group has identified a new gene that allows cancer cells to survive in the typically acidic microenvironment of a malignant tumour. They have discovered drugs that inhibit the gene in other medical conditions also selectively kill cancer cells at acidic pH, without damaging healthy tissue. This defines a novel strategy for targeting acidic tumour regions.
Latest publications
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Lactate saturation limits bicarbonate detection in hyperpolarized 13 C-pyruvate MRI of the brain.
Journal article
Bøgh N. et al, (2022), Magn Reson Med
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Assessing the effect of anesthetic gas mixtures on hyperpolarized 13 C pyruvate metabolism in the rat brain.
Journal article
Healicon R. et al, (2022), Magn Reson Med
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Supervised spatial inference of dissociated single-cell data with SageNet
Heidari E. et al, (2022)
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Molecular mechanisms governing aquaporin relocalisation
Journal article
Markou A. et al, (2022), Biochimica et Biophysica Acta - Biomembranes, 1864
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Tinnitus: at a crossroad between phantom perception and sleep
Journal article
MILINSKI L. et al, (2022), Brain Communications
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Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
Journal article
Hulikova A. et al, (2022), Basic Res Cardiol, 117
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Divergent trajectories of antiviral memory after SARS-CoV-2 infection.
Journal article
Tomic A. et al, (2022), Nat Commun, 13
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CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH.
Journal article
Michl J. et al, (2022), Cell Rep, 38
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Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents
Journal article
Hazlehurst JM. et al, (2022), Metabolism Open, 100177 - 100177
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Exclusion and Co-expression of Aversive Olfactory Long-Term Memories in Drosophila.
Journal article
Zhao B. et al, (2022), Neurosci Bull