Contact information
Research groups
Collaborators
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Duncan Sparrow
Professor of Cardiovascular Developmental Biology
Dorota Szumska
Postdoctoral Research Scientist
I have recently joined Sarah's group to work on transcriptional regulation of genes crucial for the development of mammalian vascular system.
I have many years of experience in mouse embryogenesis. In the De Val lab, my work includes generating and analysing mouse models of normal and pathological vascular specification, growth and homeostasis. In particular, I am developing a pipeline for imaging and analysing our enhancer:reporter transgenic embryos on a variety of different mutant backgrounds using High Resolution Episcopic Microscopy (HREM).
Recent publications
staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).
Journal article
Geyer SH. et al, (2017), J Anat, 230, 710 - 719
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
Journal article
Szumska D. et al, (2017), BMC Dev Biol, 17
SPP2 deficiency causes features of 1q41q42 microdeletion syndrome.
Journal article
Zak J. et al, (2016), Cell Death Differ, 23, 1973 - 1984
Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs.
Journal article
Grijzenhout A. et al, (2016), Development, 143, 2716 - 2723
Deciphering the mechanisms of developmental disorders: phenotype analysis of embryos from mutant mouse lines.
Journal article
Wilson R. et al, (2016), Nucleic Acids Res, 44, D855 - D861