Centre for Integrative Neuroscience
Neuroscience represents the largest research theme in the Department, with broad-ranging interests that include understanding how sensory information is processed in the brain and how this is affected by brain state and past experience, how neurons are formed and assembled into circuits, and how neuromuscular and neurological disorders develop, with a particular focus on the molecular mechanisms of degeneration. By bringing together cutting-edge techniques from molecular biology and genetics through the physiological study of cellular and circuit interactions to behaviour, we are addressing fundamental questions concerning the functional architecture and computational principles underlying neural processing, as well as seeking to translate this basic science into treatments for disease.
In 2018, the Department established a Centre for Integrative Neuroscience, which is located in the east wing of the Sherrington Building and extends into the adjacent Centre for Cellular and Molecular Neurobiology. A major focus of this centre is the multidisciplinary study of mammalian neural circuits, complementing the fly-based research in the Centre for Neural Circuits and Behaviour. The centre brings together our world leading expertise in the investigation of how the cells of the nervous system develop, migrate into position and assemble into specific circuits, how those cells communicate with each other and encode information, and how the circuits they form give rise to behaviour.