Sandor Szunyogh

I joined the Wade-Martins group in 2020 and have worked since to characterize the formation of the HDAC4/N-CoR/HDAC3 protein complex and its functional consequences in epigenetic gene repression, to gain insights into the underlying mechanisms of Parkinson’s disease; ultimately, to find a way to therapeutically intervene and stop the progression of the disease in an early stage. 

I gained my scientific background in Biochemistry and Molecular Cell Biology at the Eötvös Loránd Science University in Budapest, where I obtained both my B.Sc. and M.Sc. degrees. I completed my PhD in collaboration with the Hungarian Academy of Sciences, Institute of Enzymology, where I studied the interactions of the protein TPPP/p25 (p25a). Particularly, I identified the interfaces of TPPP/p25 which bind its physiological partner tubulin and its pathological partner alpha-synuclein, in order to selectively inhibit the regions affected in neurodegenerative diseases.