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Oxford Parkinson's Disease Centre Logo: the OPDC is funded by Parkinson's UK. Change attitudes. Find a cure. Join us.

The success of the Discovery Cohort is crucially dependent on the participation of people with Parkinson’s and earlier prodromal forms of Parkinson’s including individuals with the sleep disorder rapid eye-movement sleep behavior disorder (RBD). 6% of RBD subjects per year will convert to Parkinson’s or a related disorder, therefore this is a key group of people for us to study. We are also grateful to control participants and relatives of Parkinson’s subjects for their study participation.

We are pleased to announce we have been awarded a further 5 years funding to continue the Discovery Cohort study from 2021 to 2026. A huge thanks to every single participant and person, who has donated their time to the Discovery study and OPDC as a whole, guaranteeing its success!

In the new study phase from 2021, People with Parkinson’s (PwP) who have already taken part in the cohort study from 2010 to 2016 will be followed up using remote, tele-medicine follow ups. Instead of a clinic visit you may be offered a video call appointment instead (or telephone call if you do not have access to a suitable device). We have been piloting this in Oxford during 2020 and have had positive feedback from participants. The video call will take around 1 hour, and there may be opportunity for someone from your local Parkinson’s UK branch to help you set up a computer at home to facilitate you getting online for research assessments. Paper copies of the study questionnaires and freepost envelopes will continue to be available for those without access to these devices. There may be times where you will be invited to attend the clinic for an additional procedure, such as a memory test, a blood test, an MRI or skin biopsy. At anytime you can ask for more information or decline the visit. If you have any questions or concerns, please get in touch with us via parkinsons.discovery@nhs.net.

For all RBD participant visits we will still offer in-person clinic visits unless you let us know you are unable to attend. These clinics will be held either in Oxford, Cambridge or Sheffield (you can ask for more information when you are invited to your next follow up appointment). All of our relative and control participants will continue to be offered telephone follow ups as before. Further details on the new study phase are available in the OPDC cohort newsletter (Issue 11, March 2021).

  • You have been diagnosed with REM sleep Behaviour Disorder following an overnight sleep study and are willing to travel to one of our sleep research sites at Oxford, Cambridge or Sheffield.

We are no longer recruiting people with Parkinson's for this study, as we continue to follow up PwP from the original cohort of 1000 PwP, recruited from 2010 to 2016. If you are interested in taking part in other research studies, you can visit the below websites:

Parkinson's UK Take Part Hub - Find research for you

Michael J. Fox Foundation Trial Finder

Lucy Norman portraitThe experience has been fascinating and thorough, and has helped me understand my condition a bit more. - Lucy Norman
Michael Doherty portraitI wanted to take part to support the efforts my brother is making. I would like to help the medical community in their efforts to diagnose the condition earlier. - Michael Doherty
Taking part in this study gives me the satisfaction of being of some help. - Hubert Allen
Alun Evans portraitI am keen to do anything I can to help medical research.
- Alun Davies

Watch a video of Lucy and her husband Angus sharing their experience of taking part in our research project

OPDC REM behavior disorder (RBD) Discovery Cohort participant interview

This video shows Parkinson's UK's Director of Research, Dr Arthur Roach, taking part in the study here in Oxford.

We are still recruiting:

  • People diagnosed with REM sleep Behaviour Disorder. 

If you are interested in participating please do the following:

For further information, please contact the research team at:

Tel: 01865 223166
Email: parkinsons.discovery@nhs.net

Please note that we are no longer recruiting people with Parkinson's for this study. If you are interested in taking part in other research studies, you can visit the below websites:

Parkinson's UK Take Part Hub - Find research for you

Michael J. Fox Foundation Trial Finder