About Us
The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research program at the University of Oxford. The OPDC was established in February 2010 and brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our world-class research centre works to understand the earliest events in the development of Parkinson’s with an ultimate view to target the molecular mechanisms of disease with neuroprotective therapies to prevent disease onset or delay progression.
Our program is focused on the molecular pathways to Parkinson’s in order to:
- Predict the onset of Parkinson’s
- Understand the progression of Parkinson’s
- Identify potential drug targets for Parkinson's
- Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to learn more about OPDC's research:
Latest News
Upcoming Seminars
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Tuesday, 03 June 2025, 9am to 5.30pm
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Monday, 23 June 2025, 12pm to 1pm
Speakers: Associate Professor Antony Cooper
Latest publications
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The profile of gastrointestinal dysfunction in prodromal to late-stage Parkinson's disease.
Journal article
Camacho M. et al, (2025), NPJ Parkinsons Dis, 11
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Dopamine D2 receptor upregulation in dorsal striatum in the LRRK2-R1441C rat model of early Parkinson's disease revealed by in vivo PET imaging.
Journal article
Delgado-Goñi T. et al, (2025), Sci Rep, 15
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Working memory filtering at encoding and maintenance in healthy ageing, Alzheimer's and Parkinson's disease.
Journal article
Toniolo S. et al, (2025), Sci Rep, 15
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Cholinergic degeneration in prodromal and early Parkinson's: a link to present and future disease states.
Journal article
Eisenstein T. et al, (2025), Brain
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Automated quality control of T1-weighted brain MRI scans for clinical research: methods comparison and design of a quality prediction classifier
Journal article
Bhalerao GV. et al, (2025), Imaging Neuroscience
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TFEB and TFE3 have cell-type specific expression in the brain and divergent roles in neurons
Preprint
McGuinness W. et al, (2025)