About Us
The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research program at the University of Oxford. The OPDC was established in February 2010 and brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our world-class research centre works to understand the earliest events in the development of Parkinson’s with an ultimate view to target the molecular mechanisms of disease with neuroprotective therapies to prevent disease onset or delay progression.
Our program is focused on the molecular pathways to Parkinson’s in order to:
- Predict the onset of Parkinson’s
- Understand the progression of Parkinson’s
- Identify potential drug targets for Parkinson's
- Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to learn more about OPDC's research:
Latest News
Latest publications
Cerebral blood flow as a mechanistic framework across neurological disease
Journal article
Patel S. et al, (2026), Discover Neuroscience, 21
Protocol for efficient purification of endotoxin-free human recombinant tau protein
Journal article
Karabova MK. et al, (2026), STAR Protocols, 7, 104800 - 104800
Granule cells reorient cortical trajectories to separate contexts.
Journal article
Garcia-Garcia MG. et al, (2026), Nature
Regulated HSPG Signaling Directs Epicardial Behavior to Support Cardiac Formation.
Journal article
Redpath AN. et al, (2026), Circ Res
Machine learning for functional outcome prediction after vestibular schwannoma surgery: a systematic review and diagnostic test accuracy meta-analysis.
Journal article
Nischal SA. et al, (2026), J Neurooncol, 179
Population-scale subcellular proteomics reveals intracellular remodelling across the Alzheimer’s disease-resilience spectrum
Preprint
Jolly HA. et al, (2026)

