About Us
The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research program at the University of Oxford. The OPDC was established in February 2010 and brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our world-class research centre works to understand the earliest events in the development of Parkinson’s with an ultimate view to target the molecular mechanisms of disease with neuroprotective therapies to prevent disease onset or delay progression.
Our program is focused on the molecular pathways to Parkinson’s in order to:
- Understand the progression of Parkinson’s
- Predict the onset of Parkinson’s
- Identify potential drug targets for Parkinson’s
- Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to learn more about OPDC's research:
Latest News
Upcoming Seminars
Latest publications
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Evaluation of Cerebrospinal Fluid α-Synuclein Seed Amplification Assay in Progressive Supranuclear Palsy and Corticobasal Syndrome.
Journal article
Vaughan DP. et al, (2024), Mov Disord
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A worldwide study of white matter microstructural alterations in people living with Parkinson's disease.
Journal article
Owens-Walton C. et al, (2024), NPJ Parkinsons Dis, 10
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Relevance of genetic testing in the gene-targeted trial era: the Rostock Parkinson's disease study.
Journal article
Westenberger A. et al, (2024), Brain, 147, 2652 - 2667
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Concerns with the new biological research criteria for synucleinopathy.
Journal article
Boeve BF. et al, (2024), Lancet Neurol, 23, 659 - 660
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Genome-wide determinants of mortality and motor progression in Parkinson's disease.
Journal article
Tan MMX. et al, (2024), NPJ Parkinsons Dis, 10
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Psychosis as a disorder of muscarinic signalling: psychopathology and pharmacology.
Journal article
McCutcheon RA. et al, (2024), Lancet Psychiatry