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Sleep and Phantom Sounds: Investigating tinnitus in the sleep ferret
Phenotype Magazine article on page 9
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Royal National Institute for Deaf People
Funder
- Research Careers
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Linus Milinski
Postdoctoral Research Scientist
Why do we sleep?
We spend about a third of our life asleep, yet scientists are still trying to unravel the mystery behind this vital activity. While it is widely agreed that the brain is central to sleep regulation, we are still uncertain about where and how our need for sleep is regulated.
My research focuses on understanding how the circuitry in a central part of the brain, specifically in the cerebral cortex, influences sleep-related brain activity and the build-up of sleep pressure. To investigate this, I combine genetical manipulation of brain activity with electrophysiological recordings, behavioural paradigms and computational analysis.
In my previous research, I investigated multiple facets of sleep regulation such as how waking experience modulates sleep pressure and how pathological phantom percepts generated by the brain interact with sleep.
Biography
I am a Postdoctoral Research Scientist working with Vladyslav Vyazovskiy and Zoltán Molnár. I completed a DPhil in tinnitus and sleep research supervised by Victoria Bajo-Lorenzana, Vladyslav Vyazovskiy and Fernando Nodal at the University of Oxford. Previously, I conducted an MSc. project on sleep-dependent sound processing in the group of Livia de Hoz at the Max-Planck-Institute for Experimental Medicine, after having obtained a BSc. in Biology at the Georg-August University in Göttingen, Germany.
I am also a science writer with articles contributed to The Conversation, The Oxford Scientist, The Oxford Student, Phenotype Magazine and Oxford Scholastica Academy. I was editor for the Oxford Scientist and produced the Frontiers of Science print issue. I am currently an editor and the Events Lead for research.careers.org. Moreover, I taught neuroscience classes for Balliol College Oxford and Oxford Scholastica Academy.
Recent publications
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Sound disrupts sleep-associated brain oscillations in rodents in a meaning-dependent manner
Journal article
van Kronenberg P. et al, (2022), Scientific Reports, 12
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Tinnitus: at a crossroad between phantom perception and sleep
Journal article
MILINSKI L. et al, (2022), Brain Communications
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Sound disrupts sleep-associated brain oscillations in rodents according to its meaning
Journal article
van Kronenberg P. et al, (2021), bioRxiv
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Somnotate: A probabilistic sleep stage classifier for studying vigilance state transitions
Journal article
Brodersen PJN. et al, (2021)
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Diazepam effects on local cortical neural activity during sleep in mice.
Journal article
McKillop LE. et al, (2021), Biochem Pharmacol, 191
Sleep and Tinnitus: Action on Hearing Loss Tinnitus Special
- White Noise - Tinnitus Special Supplement.pdf
- PDF document 1.6 MB
Around 10% of people in the UK are thought to have persistent Tinnitus - and for 1% of the population, the condition is so intrusive that it severely affects their quality of life, leading to anxiety, depression and problems sleeping. Action on Hearing Loss is funding Linus to tackle when and where in the brain tinnitus develops, and published an article about his research in a special for Tinnitus Week (page 13) in their January ITL Newsletter.