News

Failing hearts can use different fuels, and prefer fat over sugar

31 May 2023

An exciting new collaborative study from RDM and DPAG researchers has found that fat metabolism could be the key to tackling heart failure.

Portrait outside the Burdon Sanderson Cardiac sciences Centre

Manuela Zaccolo is an Elected Member of Academia Europaea

24 May 2023

Congratulations are in order to Professor Manuela Zaccolo on being awarded Membership of the Academia Europaea (MAE).

Manuela Zaccolo honoured by leading Italian Academy

17 April 2023

Congratulations are in order to Professor Manuela Zaccolo on being elected Fellow of the Istituto Veneto di Scienze, Lettere ed Arti, one of the most prestigious Academies in Italy.

Unlocking the Secrets of cAMP Signalling in the Heart: A Pathway to Targeted Therapeutics

9 March 2023

A new Zaccolo group study has revealed key new insights into the role of cAMP signalling in both healthy and disease settings within the heart. They have identified new cAMP nanodomains in cardiac muscle cells that have far reaching implications for the treatment of heart disease.

New blood test from DPAG cardiac researchers could save lives of heart attack victims

31 January 2023

Researchers from the Herring group have developed a blood test that measures stress hormone levels after heart attacks. The test – costing just £10 – could ensure patients receive timely life-saving treatment.

Strong performance for DPAG cardiac research at the Oxford BHF CRE Annual Symposium

30 November 2022

Congratulations are in order for Kaitlyn Dennis, Dr Ni Li and Dr KC Park on their awards at this year's major showcase for Oxford's British Heart Foundation funded researchers.

Peregrine Green wins HRC 2022 Young Investigator Award

11 October 2022

Congratulations are in order for Dr Peregrine Green, who has received the Young Investigator award at the Heart Rhythm Congress 2022.

Kaitlyn Dennis to receive the William C Stanley Early Investigator Award

22 September 2022

Congratulations are in order for DPhil student Kaitlyn Dennis, who has been awarded the William C Stanley Early Investigator Award. The award highlights the scientific accomplishments of promising young researchers and is a major focus of the Annual Meeting of the Society for Heart and Vascular Metabolism.

Neil Herring to give prestigious Bayliss-Starling Prize Lecture

30 June 2022

The annual Prize Lecture from The Physiological Society will provide an opportunity to highlight the importance of the Herring lab's work into the nervous system’s critical role in cardiovascular health and disease.

BHF Senior Fellowship renewal for Duncan Sparrow could pave the way to revealing unknown causes of heart defects in babies

27 June 2022

Congratulations are in order for Associate Professor Duncan Sparrow, who has been awarded a renewal of his British Heart Foundation Senior Basic Science Research Fellowship. The award will fund crucial investigations into little understood environmental risk factors of congenital heart disease, and could one day lead to new therapeutic strategies.

Peregrine Green honoured by British Cardiovascular Society

9 June 2022

Congratulations are in order for Dr Peregrine Green, who has won a prestigious abstract award at the BCS Annual Conference.

DPAG researchers showcased at premier European Society of Cardiology meeting

5 May 2022

DPAG scientists across four research groups were highlighted at the major annual European Society of Cardiology basic science conference (FCVB 2022). Congratulations are in order for Dr KC Park on receiving the Young Investigator Award and to Dr Elisabetta Gamen on winning the Moderated Poster Prize.

Map of nuclear and cytoplasmic pH recorded in neonatal cardiac cells incubated in various medium pH: 6.24, 6.49, 6.80. 6.98, 7.10 and 7.45. This is colour coded on a scale from 6.1 - 7.6 pH.

The effect of nuclear pH on cardiac gene expression

13 April 2022

Research led by Dr Alzbeta Hulikova and Professor Pawel Swietach has, for the first time, described the potential regulation of nuclear acid-base chemistry in neonatal and adult cardiomyocytes, and explained its relevance in the context of heart physiology and pathology.

Drug could help diabetic hearts recover after a heart attack

20 October 2021

New research led by Associate Professor Lisa Heather has found that a drug known as molidustat, currently in clinical trials for another condition, could reduce risk of heart failure after heart attacks.

DPAG Researchers honoured for their work in cardiac metabolism

27 September 2021

Kaitlyn Dennis, Ujang Purnama and Kerstin Timm have won prizes across each of the three award categories at this year’s Society for Heart and Vascular Metabolism conference, demonstrating DPAG's continued excellence in cardiac metabolism research.

Richard Tyser and Jack Miller honoured by the British Society of Cardiovascular Research

14 September 2021

Dr Richard Tyser is this year’s winner of the Bernard and Joan Marshall Early Career Investigator Prize, and Dr Jack Miller has received a runner-up award, at the British Society of Cardiovascular Research Autumn Meeting.

Iron deficiency anaemia in early pregnancy increases risk of heart defects, suggests new research

8 June 2021

In animal models, iron deficient mothers have a greatly increased risk of having offspring with congenital heart disease (CHD). The risk of CHD can be greatly reduced if the mother is given iron supplements very early in pregnancy. Additionally, embryos from a mouse model of Down Syndrome were particularly vulnerable to the effects of maternal iron deficiency, leading to a higher risk of developing severe heart defects.

New research grant to Pawel Swietach to further understanding of propionic acidemia

26 March 2021

A new collaborative project led by the Swietach group funded by the Propionic Acidemia Foundation will investigate the disease mechanisms and risk factors for cardiac disease caused by a severe inherited disorder.

New MRI technique could detect early signs of heart failure in cancer patients following chemotherapy

19 November 2020

New research led by Oxford BHF CRE Intermediate Transition Fellow Dr Kerstin Timm shows that a recently developed imaging technique pioneered by the Tyler Group can detect early metabolic changes in the heart caused by a commonly used chemotherapy drug, which is known to increase risk of heart failure in cancer survivors.

Two major BHF awards to Neil Herring pave the way to new treatments for heart attack patients

12 November 2020

Associate Professor Neil Herring has been awarded a Senior Clinical Research Fellowship and a Project grant from the British Heart Foundation to further critical research into the mechanisms behind heart attacks and heart failure and potential drugs to combat them. Given the 50% reduction in research investment this year from the BHF due to the impact of COVID-19, Prof Herring is to be congratulated on these awards.

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