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« Back to NewsNew Paper on Layer 6b published by Professor Zoltan Molnar and colleagues in Neuron
15 December 2023
Molnar Group News Publication Research
Professor Zoltan Molnar has collaborated with colleagues on a new paper in Neuron.
Breakthrough Insights: Diffusion-Limited Oxygen Release from Stored Blood Unveiled in New Article
5 December 2023
In a new article published in Blood, the journal of the American Society of Hematology, researchers from the Department of Physiology, Anatomy, and Genetics (DPAG) and The Nuffield Department of Surgical Sciences (NDS) at the University of Oxford present compelling evidence that challenges established notions about oxygen delivery during organ perfusion.
Researchers characterise the landscape of somatic mutations among acid-base transporters in human cancers
1 December 2023
A new paper lead by DPhil student Bobby White and Professor Pawel Swietach from DPAG’s Swietach Group explores the role that somatic mutations affecting plasma membrane acid-base transporters play in human cancer evolution. The team identify acid-base transporters that are essential to cancer cell survival, and those where somatic mutations are likely to play a driving role in certain cancer types.
Pawel Swietach and KC Park publish paper in Nature Cardiovascular Research
24 November 2023
Working with collaborators from across Oxford (Thomas Milne, Nick Crump, James McCullagh, Roman Fisher, Marjorie Fournier), in Cambridge (Sophie Trefely), and at Great Ormond Street Hospital (Steve Krywawych), Pawel Swietach and KC Park working at DPAG have published a new article, 'Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation', in Nature Cardiovascular Research.
Rui Ponte Costa receives EPSRC New Investigator Award
15 November 2023
Awards and Honours Costa Group News Research
Rui Ponte Costa has received an EPSRC New Investigator award for research exploring Cerebellum-inspired parallel deep learning
The King group has published a new paper in the journal eLife
9 November 2023
Professor Andrew King and members of his research group have just published a new paper ‘Hierarchical temporal prediction captures motion processing along the visual pathway’ in the journal eLife.
First digital atlas of human fetal brain development published
1 November 2023
The first digital atlas showing how the human brain develops in the womb has been published by a global research team led by the University of Oxford.
Oxford researchers make first step in engineering human cortical columns for brain repair
25 October 2023
A collaborative team of DPAG, Chemistry and Oxford Martin School (OMS) researchers have achieved the first step to printing the 6 distinct layers of the cerebral cortex as part of a landmark project seeking to repair brain damage by transplanting replicated ‘pre-organised’ printed neural tissue.
Pioneering new software to analyse intracellular calcium signals
1 September 2023
Cell Physiology Postdoctoral Publication Research
A collaborative team of UC Davis and University of Oxford researchers have developed an innovative new software tool – SparkMaster 2 – which will enable automatic analysis of calcium sparks which are known to cause cardiac arrythmias in a variety of disease settings. First and co-corresponding author Dr Jakub Tomek, who is a Sir Henry Wellcome Fellow based in DPAG's Zaccolo group, conducted this research as part of his fellowship year spent at UC Davis.
International collaboration aims to reveal key insights into Postpartum Depression
29 August 2023
Integrative Neuroscience Research
DPAG is proud to announce a new collaboration, alongside St Anne's College and the Pranaiya and Arthur Magoffin Foundation (PAM Foundation), to research postpartum depression (PPD) and other perinatal mental health illnesses.
Can 3D models of brain-on-chip help in developing new treatments?
19 July 2023
Outreach Research Salman Group News Wade-Martins Group News
Fascinating new TEDx Talk from Departmental Research Lecturer and Leverhulme Fellow Dr Mootaz Salman.
Exploring the importance of early brain development
12 July 2023
Integrative Neuroscience Long Read Molnar Group News Research
Mental health is not written in the stars – but some conditions can be determined even before birth and the origins of some vulnerabilities may lie in the first few months of life, says Professor Zoltán Molnár. Part of the University of Oxford's 'Brain and mental health' campaign.
Researchers discover how cancer cells adapt under acidity
27 June 2023
Cell Physiology EDI News Postdoctoral Publication Research
New research led by Dr Johanna Michl and Professor Pawel Swietach has solved the longstanding mystery of how cancer cells are able to maintain a relatively alkaline intracellular pH, despite being surrounded by an acidic environment. A raised intracellular pH is required for cancer progression because it allows cancer cells to efficiently proliferate and metastasise. However, until now the exact molecular mechanism underlying this adaptation was unknown.
BHF Fellowship extension for Lisa Heather to further our understanding of metabolic dysfunction in diabetes
16 June 2023
Awards and Honours Cardiac Theme EDI News Heather Group News Research
Congratulations are in order for Associate Professor Lisa Heather, who has been awarded an extension of her British Heart Foundation Intermediate Basic Science Research Fellowship. The extension recognises her successful research on the impact of abnormal metabolism in diabetes on the heart and will prepare her for progression to a Senior Fellowship.