31 January 2020
DPAG's Dr Jakub Tomek and Professor Blanca Rodriguez's Computational Cardiovascular Science Team have developed a new computer model that recreates the electrical activity of the ventricles in a human heart. In doing so, they have uncovered and resolved theoretical inconsistencies that have been present in almost all models of the heart from the last 25 years and created a new human heart model that could enable more basic, translational and clinical research into a range of heart diseases and potentially accelerate the development of new therapies.
30 January 2020
An immune cell is shown for the first time to be involved in creating the scar that repairs the heart after damage. The Riley Group study was funded by the British Heart Foundation and led by BHF CRE Intermediate Transition Research Fellow Dr Filipa Simões.
8 January 2020
For many years, we have been using beta-blockers to neutralise a specific stress hormone and prevent dangerous heart rhythms following a heart attack. However, a new study led by Associate Professor Neil Herring and published in the European Heart Journal has uncovered evidence for an additional stress hormone acting as a key trigger for dangerous heart rhythms that is not currently targeted by these drugs.
7 January 2020
UCLA Researchers in collaboration with DPAG researchers from the Paterson and Herring Groups have identified a biomarker for increased risk of early mortality in patients with heart failure. Associate Professor Neil Herring is senior author.
21 October 2019
Congratulations are in order to Professor Manuela Zaccolo on being elected Fellow of the Royal Society of Biology.
17 October 2019
Congratulations are in order to Matthew Kerr, Andia Redpath, Susann Bruche, KC Park and Minahil Mujahid for their achievements at this major showcase for Oxford's British Heart Foundation funded Researchers.
15 October 2019
The award recognises and solidifies Professor Tyler's collaborative work with the MR Research Centre, part of the Department of Clinical Medicine at the University of Aarhus.
14 August 2019
This year's "Reflections of Research" competition, run by the British Heart Foundation, selects "The Forming Heart" by Dr Richard Tyser as the Judge's runner-up
22 July 2019
A collaborative paper from the De Val and Smart Groups has established multiple regulatory pathways responsible for the formation of blood vessels in the developing heart. In doing so they have identified a crucial pathway that is repressed in the adult heart after injury, which may hold the key to a new and improved strategy for repair.
12 July 2019
During the emergency procedure used to reopen the blocked artery causing a heart attack, smaller "micro" blood vessels can remain constricted causing significant damage. A new study led by Associate Professor Neil Herring and published in the European Heart Journal has established a key cause behind this constriction and identified a potential therapeutic target to block the mechanism behind it.
Sarah De Val set to expand critical research into endothelial cell dysfunction in cardiovascular disease
12 July 2019
Prof Sarah De Val in collaboration with Dr Gillian Douglas from the Radcliffe Department of Medicine has received a grant from the John Fell Fund to support their work investigating the behaviour of different endothelial regulatory pathways during disorders of the cardiovascular system.
Cardiac, metabolism and cell physiology researchers come together for Integrative Physiology Theme Day
3 July 2019
The Department's third and final theme day of the year culminated in a series of exciting internal talks from a diverse range of research groups covering all aspects of integrative physiology. From diabetes to iron deficiency, from pH physiology to cancer cells, the talks showcased the huge breadth of science studied across DPAG.
BHF Senior Fellowship renewal for Nicola Smart paves the way for stimulating vessel growth to repair damaged hearts
14 June 2019
Congratulations are in order for Associate Professor Nicola Smart, who has been awarded a renewal of her British Heart Foundation Senior Basic Science Research Fellowship. The award will fund research investigating the processes behind blood vessel growth in order to understand how to stimulate heart repair after injury.
7 June 2019
Congratulations are in order to Smart Group members Dr Tonia Thomas and Sonali Munshaw.
7 June 2019
Congratulations are in order to Associate Professor Neil Herring on being made a Fellow of the Royal College of Physicians.
7 June 2019
A series of internal talks demonstrated an extensive breadth of research within the Development and Cell Biology Theme that tackles the questions fundamental to understanding evolution, growth, organ formation, the onset of disease and tissue regeneration. DPAG Researchers were also joined by two external speakers presenting their research into age-related angiocrine signals and stem cell strategies for lung development.
3 June 2019
A new discovery from the Lakhal-Littleton Group on how iron deficiency affects the vasculature of the lung could hold the key to improving treatment of pulmonary arterial hypertension.
25 April 2019
Congratulations are in order for DPhil student Matthew Kerr, who has been awarded the William C Stanley Early Investigator Award. The award highlights the scientific accomplishments of promising young researchers and is a major focus of the Annual Meeting of the Society for Heart and Vascular Metabolism.
29 March 2019
Congratulations are in order for DPhil student, Rita Alonaizan, who has won Phenotype's Michaelmas 2018 cover competition
BHF Senior Fellowship renewal for Damian Tyler paves the way for improving diagnostic imaging in Heart Disease
29 March 2019
Congratulations are in order for Professor Damian Tyler, who has been awarded a renewal of his British Heart Foundation Senior Fellowship. The award will fund a project designed to develop a new imaging approach, enabling doctors to diagnose heart diseases more accurately.