Contact information
Research groups
Collaborators
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Pawel Swietach
Professor of Physiology
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Manuela Zaccolo
Deputy Head of Department
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Heidi de Wet
Associate Professor of Physiology
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Francis Szele
Associate Professor of Developmental Biology
Colleges
Liron Boyman
PhD
Group Leader and BHF Intermediate Fellow
- Principal Investigator at Oxford BHF Centre of Research Excellence (CRE)
Key publications
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Voltage-energized calcium-sensitive ATP production by mitochondria
Journal article
Wescott AP. et al, (2019), Nature Metabolism, 1, 975 - 984
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Calcium and bicarbonate signaling pathways have pivotal, resonating roles in matching ATP production to demand
Journal article
Greiser M. et al, (2023), eLife, 12
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Regulation of Mitochondrial ATP Production: Ca2+ Signaling and Quality Control
Journal article
Boyman L. et al, (2020), Trends in Molecular Medicine, 26, 21 - 39
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How the mitochondrial calcium uniporter complex (MCU cx ) works
Journal article
Boyman L. and Lederer WJ., (2020), Proceedings of the National Academy of Sciences, 117, 22634 - 22636
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Ryanodine receptor stabilization therapy suppresses Ca2+- based arrhythmias in a novel model of metabolic HFpEF
Journal article
Kaplan AD. et al, (2024), Journal of Molecular and Cellular Cardiology, 195, 68 - 72
Recent publications
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Constitutive deletion of the obscurin-Ig58/59 domains induces atrial remodeling and Ca2+-based arrhythmogenesis.
Journal article
Grogan A. et al, (2025), JCI Insight, 10
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Outer mitochondrial membrane E3 Ub ligase MARCH5 controls de novo peroxisome biogenesis
Journal article
Verhoeven N. et al, (2025), Developmental Cell, 60, 40 - 50.e5
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Ryanodine receptor stabilization therapy suppresses Ca2+- based arrhythmias in a novel model of metabolic HFpEF
Journal article
Kaplan AD. et al, (2024), Journal of Molecular and Cellular Cardiology, 195, 68 - 72
-
Na+/K+ATPase-Cav1.2 nanodomain differentially regulates intracellular [Na+], [Ca2+] and local adrenergic signaling in cardiac myocytes
Preprint
Karbowski M. et al, (2023)
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Outer mitochondrial membrane E3 Ub ligase MARCH5 controls mitochondrial steps in peroxisome biogenesis
Preprint
Verhoeven N. et al, (2023)