ECG Inverse Techniques and Validation

We are working in collaboration with Dr Andrew Pullan from the Electrical Imaging Research Group (Bioengineering Institute, Auckland University, New Zealand), towards validating computational approaches to inverse electrocardiography. Of particular interest, is a novel activation inverse approach formulated by Greensite et al. A computational implementation of this theoretical approach has recently been completed, but the accuracy and sensitivity of this algorithm for the in-vivosituation recordings remains to be determined.

We are developing an integrated experimental and computational framework to provide comprehensive sets of in-vivorecordings, under normal and pathological conditions, with which we plan to refine and validate the computational activation inverse approach.

Selected publications:

Pullan, A.J., Cheng, L.K., Nash, M.P., Bradley, C.P. & Paterson, D.J., (2001). Non-invasive electrical imaging of the heart - theory and model development. Ann. Biomed. Eng. 29(10): 817-836. [Abstract]

There are also some posters and conference abstracts outlining this on-going research.

Page written by Dr Martyn Nash