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Inside the Wade-Martins Lab for World Parkinson's Day

8 April 2019

This week we raise awareness of Parkinson's Disease and related disorders with a unique video insight into the work of the Wade-Martins Group.

This week DPAG is marking World Parkinson's Day, which takes place on Thursday 11 April 2019, with an inside look into the Wade-Martins Laboratory.

The Wade-Martins Group conducts critical research into several neurodegenerative diseases, including Parkinson's Disease, Alzheimer's Disease and Friedreich's Ataxia, with the aim to understand the molecular mechanisms of these disorders and help develop new treatments.

This video is narrated by Professor Richard Wade-Martins, with contributions from Charmaine Lang, Dayne Beccano-Kelly, Peter Kilfeather, Phillippa Carling, Gabriela Vilema Enriquez and former members of the team, Gabriele Corda, Rebecca Wallings and Marta Cherubini.

Can humans hibernate?

20 March 2023

Illuminating new TEDx Talk from Professor of Sleep Physiology Vladyslav Vyazovskiy

New insights into chemogenetic designer drugs to enhance our study of behaviour

10 March 2023

A collaborative team of researchers in DPAG and Pharmacology led by Dr Lukas Krone have uncovered striking new data demonstrating that two widely used designer drugs used to turn populations of neurons on and off in the brain cause unexpected effects on sleep. These results demonstrate a critical need to improve chemogenetic approaches in behavioural studies.

Unlocking the Secrets of cAMP Signalling in the Heart: A Pathway to Targeted Therapeutics

9 March 2023

A new Zaccolo group study has revealed key new insights into the role of cAMP signalling in both healthy and disease settings within the heart. They have identified new cAMP nanodomains in cardiac muscle cells that have far reaching implications for the treatment of heart disease.

Key exosome subtype in cancer progression identified

8 March 2023

Collaborative work from DPAG and Oncology researchers has revealed a potential new pathway to block the production of a specific group of exosomes made in the cell’s recycling system that can promote the growth of cancerous tumours.

Inaugural Fellowship to Charmaine Lang paves the way to improved human models for Parkinson's drug discovery

3 February 2023

Congratulations are in order for Departmental Research Lecturer Dr Charmaine Lang who has been awarded the first jointly funded Senior Research Fellowship from Parkinson’s UK and Rosetrees Trust. With this award, Dr Lang will develop complex new induced pluripotent stem cell (iPSC) models that target the interaction between dopamine neurons and astrocytes in the brain and how these fail in the context of Parkinson's.