Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Congratulations are in order for Postdoctoral Research Scientist Dr Samuel Malone who was been awarded the Marie Sklodowska Curie Individual Fellowship, funded by the European Commission.

Samuel Malone

Dr Samuel Malone, a Postdoctoral Research Scientist in the Domingos Group, has been awarded the Marie Sklodowska Curie Individual Fellowship, funded by the European Commission, to fund the next two years of his research.

The sympathetic nervous system innervates all peripheral tissues, including adipose tissue, with neuro-adipose junctions mediating lipolysis and fat mass reduction. In response to a single stimulus, sympathetic responses are tissue-specific although the neuroanatomical origins and what mediates this heterogeneity is unknown.

Dr Malone aims to understand the innervation of this system and how maternal environment may regulate its development.

To do so, he will use viral tracers coupled with tissue clearing to develop a molecular map of adipose tissue and its sympathetic innervation. He will also functionally manipulate these neurons using a double-conditional chemogenetic mouse model that will allow the targeting and activation of a subpopulation of sympathetic neurons that innervate adipose tissue.

These studies will help to explain how adipose architecture and physiology change with the onset of obesity; informing the basis for metabolism and peripheral neuroscience research, and becoming a key resource for future physiological and mechanistic studies.

This fellowship will give serious momentum to my research and hopefully allow us to develop new and exciting theories about the sympathetic control of obesity. The opportunity to conduct it here in a world leading department such as DPAG with Associate Professor Ana Domingos is a great honour. - Dr Malone

More information on the Marie Sklodowska Curie Individual Fellowship is available here.

Similar stories

New blood test from DPAG cardiac researchers could save lives of heart attack victims

Researchers from the Herring group have developed a blood test that measures stress hormone levels after heart attacks. The test – costing just £10 – could ensure patients receive timely life-saving treatment.

Mootaz Salman set to target new treatments for stroke

The Chief Scientist Office of the Government of Scotland has awarded a collaborative grant of £298,966 to Dr Mootaz Salman to seek new therapeutic avenues to treat stroke.

Gero Miesenböck awarded 2023 Japan Prize

Congratulations are in order for Professor Gero Miesenböck, who has been awarded the 2023 Japan Prize in the field of Life Sciences, together with Professor Karl Deisseroth, for pioneering work in the field of optogenetics.

Mootaz Salman receives prestigious science award from Iraq

Congratulations are in order for Dr Mootaz Salman, who has received the National Medal of Distinctive Scientific Achievement by the Government of Iraq.

Professor Denis Noble awarded the Lomonosov Gold Medal

The Russian Academy of Sciences has awarded its highest accolade, the Lomonosov Gold Medal, to Emeritus Professor Denis Noble CBE, FRS.