Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we will assume that you are happy to receive all cookies and you will not see this message again. Click 'Find out more' for information on how to change your cookie settings.

As part of its commitment to developing better medicines for Duchenne Muscular Dystrophy (DMD), WAVE has extended its ongoing research collaboration with the University of Oxford to advance stereopure nucleic acid therapies for DMD across exons.

microRNA array identifying extracellular microRNAs elevated in mdx mouse serum and normalised following peptide-conjugated oligonucleotide therapy

 microRNA array identifying extracellular microRNAs elevated in mdx mouse serum and normalised following peptide-conjugated oligonucleotide therapy

Through the collaboration, renowned researcher Matthew Wood and his team will continue to work with WAVE to use the company’s proprietary platform to enhance oligonucleotide approaches, including exon-skipping, to address the rare genetic muscle disease.
 
“The data we have seen to date using WAVE’s novel approach to exon-skipping in DMD is very promising. I believe that academia and industry, working together, may be on the verge of a veritable medical revolution where we can potentially effectively and durably treat genetically based diseases such as DMD,” said Professor Wood.

“Collaborations between academia and industry are critical now more than ever in order to collectively harness the latest scientific advancements to rapidly progress therapies for patients. We look forward to expanding our collaboration with the WAVE team and advancing the potential and benefits of stereopure oligonucleotide approaches for DMD.”

Read more

Similar stories

Cortex may regulate the need for sleep

Why we sleep, and the processes behind sleep, are amongst the most interesting questions in modern neuroscience. Researchers at the University of Oxford, including DPAG's Molnár and Vyazovskiy group scientists, have now uncovered a new target for sleep investigations within the mammalian brain – the cerebral cortex. The paper, first authored by Dr Lukas Krone, was published today in Nature Neuroscience.

Reducing fat in the diabetic heart could improve recovery from heart attack

New research from the Heather Group has shown that in type 2 diabetes an overload of lipids reduces the heart’s ability to generate energy during a heart attack, decreasing chances of recovery.

The brain’s one-sided teaching signals

A new study by the Lak group reveals a novel facet of dopamine signalling during visual decision making.

Fellowship awarded to Huriye Atilgan to enhance our understanding of value-based decision-making

Congratulations are in order for Postdoctoral Research Scientist Dr Huriye Atilgan who has been awarded a prestigious Sir Henry Wellcome Postdoctoral Fellowship funded by the Wellcome Trust.

The future of stroke treatment

A team of international collaborators including DPAG's Dr Mootaz Salman has been researching a promising new therapeutic for the treatment of strokes and other brain injuries.