Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

DPAG is the host Department for the annual Oxosome meetings, which bring together researchers from across Oxford with an interest in cell communication involving exosomes and other extracellular vesicles.  

The third annual meeting of Oxosome: the extracellular vesicle group organised by Deborah Goberdhan (DPAG), Dave Carter (Oxford Brookes), Eduard Willms (DPhil student, Wood lab, DPAG) and Maria Laura Tognoli (DPhil student, O’Neill lab, Dept of Oncology) was held on the afternoon of Thursday 1 November 2018 in the Sherrington Large Lecture Theatre with around 120 people participating.  

The talks showcased the quality and breadth of local research on extracellular vesicles, with speakers from a wide range of departments:  DPAG, Sir William Dunn School of Pathology, Kennedy Institute of Rheumatology, Dept of Oncology, Radcliffe Dept of Medicine, Nuffield Dept of Clinical Neurosciences and Biological and Medical Sciences at Oxford Brookes.  The talks spanned all the way from fundamental studies of vesicle biology to clinical disorders, including myocardial infarction, cancer, and neurodegenerative disease.

There was plenty of opportunity for interaction and discussion of collaborative work during the coffee break and subsequent wine reception.

Generous sponsorship from DPAG, IZON Science Ltd, EVOX Therapeutics Ltd, NanoView Bios, ONI Ltd and Analytik Ltd enabled the meeting to be held free of charge.

Similar stories

Key cause of type 2 diabetes uncovered

Research led by Dr Elizabeth Haythorne and Professor Frances Ashcroft reveals high blood glucose reprograms the metabolism of pancreatic beta-cells in diabetes. They have discovered that glucose metabolites, rather than glucose itself, are key to the progression of type 2 diabetes. Glucose metabolites damage pancreatic beta-cell function, so they are unable to release enough of the hormone insulin. Reducing the rate at which glucose is metabolised, and these glucose metabolites build up, can prevent the effects of hyperglycaemia.

New study shows clinical symptoms for Alzheimer’s can be predicted in preclinical models

Establishing preclinical models of Alzheimer’s that reflect in-life clinical symptoms of each individual is a critically important goal, yet so far it has not been fully realised. A new collaborative study from the University of Oxford has demonstrated that clinical vulnerability to an abnormally abundant protein in Alzheimer’s brain is in fact reflected in individual patient induced pluripotent stem cell-derived cortical neurons.

Updating the circuit maps of the sympathetic neural network

A new review from Professor Ana Domingos’ lab and colleagues offers a fresh modern viewpoint on sympathetic neurons and their relation to immune cells and obesity.

New Pfizer grant paves the way to a better understanding of how body fat is controlled

Professor Ana Domingos has been awarded a highly competitive independent research grant from Pfizer to discover ‘the role of Sympathetic-associated Perineurial barrier Cells in obesity’.

Collaborative MRC grant paves the way to new therapeutic targets for stress and anxiety disorders

Dr Armin Lak, Associate Professor Ed Mann and Professor Zoltán Molnár have been awarded a £733K Project Grant from the Medical Research Council on “Orexinergic projections to neocortex: potential role in arousal, stress and anxiety-related disorders”.