This new funding builds on an initial £5M investment from Parkinson’s UK to researchers at the Oxford Parkinson’s Disease Centre (OPDC) in 2010.
One in 500 people in Oxfordshire have Parkinson's – a neurological condition which can leave people struggling to walk, speak and sleep, and which has no cure.
By 2020 the multidisciplinary team at Oxford hopes to use the £6 million to find new drugs to slow, or even stop Parkinson's, using a 'brain cell bank' they have developed to identify promising new drug targets. They also want to improve how to diagnose and monitor Parkinson's using new technology, such as smartphone apps.
In the last five years, the team has developed one of the largest studies of people living with Parkinson's anywhere in the world, leading to progress in understanding why brain cells die and in detecting early changes in patients before full symptoms occur. Working with Thames Valley patients the team have created a tool to detect early stage Parkinson's with 85% accuracy using brain imaging.
Professor Richard-Wade Martins, lead researcher at the OPDC, said of receiving the funding: 'In the last five years we've made remarkable progress. We've built a study integrating work in the clinic and the laboratory like nowhere else in the world. Alongside this, our program to change cells from patients' skin into brain cells using cutting-edge stem cell technology has allowed us to gain completely new insights about Parkinson's and how it develops.
We’re delighted the new funding from Parkinson’s UK will secure the future of this and other vital projects.'