Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The post is in association with a Tutorial Fellowship at Exeter College.

I am delighted to announce that Associate Professor Neil Herring has been appointed to the APTF in association with Exeter College. Neil undertook his medical training in Oxford and completed his DPhil in the department. He is an Honorary Consultant Physician in Cardiovascular Medicine and was recently made a Fellow of The Royal College of Physicians. He will continue to undertake some clinical duties, but his research will be based in the department. - Head of Department, Professor David Paterson

NeilherringAPTFnewsembed.jpgA heart attack is caused when the blood supply to the heart becomes blocked. Many people still die from this condition owing to life-threatening heart rhythms or heart failure causing a weakened heart. After 50 years of research, beta-blockers are the only type of drug we have found that prolongs life after a heart attack by preventing dangerous heart rhythms. These drugs target norepinephrine, a chemical that can trigger dangerous heart rhythms when the heart is damaged. Norepinephrine is a type of “neurotransmitter” - chemicals released by a specific group of nerves.  

Associate Professor Neil Herring's research group, funded by the British Heart Foundation, has discovered that the same group of nerves also release a neurotransmitter called neuropeptide-Y (NPY), and that levels of NPY within the heart are very high following a heart attack and during heart failure. Prof Herring and his team has shown that NPY can trigger dangerous heart rhythms and worsen heart failure by further restricting the heart’s blood supply. 

Associate Professor Neil Herring said: "The goal of our ongoing research is two-fold: to discover whether standard blood samples taken from veins to measure NPY can help doctors identify patients at highest risk of death, and to better understand the role that NPY plays in controlling the heart, blood vessels and nerves so that drugs can be made to combat its actions."

Over the summer, a major new study led by Prof Herring established a new approach to reducing damage after a heart attack. It was published in a paper entitled Neuropeptide-Y causes coronary microvascular constriction and is associated with reduced ejection fraction following ST-elevation myocardial infarction in the European Heart Journal. 

The department would like to congratulate Prof Herring on his appointment as Associate Professor in Cardiovascular Physiology and Tutorial Fellow at Exeter College.

Similar stories

Tribute to Sir Wilfrid Le Gros Clark FRS displayed in Sherrington

The bronze portrait bust created by Sir Jacob Epstein was originally presented to the Department of Human Anatomy to mark the occasion of Sir Wilfrid Le Gros Clark's silver jubilee as Dr Lee's Professor of Anatomy.

Professor Dame Frances Ashcroft to receive Vanderbilt Prize in Biomedical Science

The Vanderbilt Prize in Biomedical Science recognises women scientists with a stellar record of research accomplishments who also have made significant contributions to mentoring other women in science.

Professor Sir Chris Whitty brings greater understanding of epidemics to Oxford

Chief Medical Officer of England Professor Sir Chris Whitty KCB FMedSci delivers the Sherrington Prize Lecture: Public Understanding of Science to an audience of Oxford staff and students.

Annie Park to advance our understanding of how the brain encodes reward with new Wellcome Trust Award

Congratulations are in order for Postdoctoral Fellow Dr Annie Park who has been awarded a prestigious Wellcome Early-Career Award.

Physiological Society award to support prestigious CAJAL course for Raffaele Sarnataro

Congratulations are in order for Dr Raffaele Sarnataro who has been awarded a Professional Development Award by The Physiological Society. The award will support Dr Sarnataro’s selected participation on the Experimental Neuroscience Bootcamp 2023 delivered by the CAJAL Advanced Neuroscience Training Programme.