Luana Campos Soares
Postdoctoral Research Scientist
My work bridges molecular neuroscience and stem cell biology to explore brain injury and disease, with a particular emphasis on regenerative approaches. I develop and apply in vitro and in vivo models to investigate mechanisms of neural repair, including the use of human pluripotent stem cells and bioengineered cortical constructs. Currently, I’m also focused on understanding blood-brain barrier (dys)function and brain water homeostasis in CNS pathologies.
BIOGRAPHY
I previously worked on The Oxford Martin Programme on 3D Printing for Brain Repair, developing and characterising 3D cortical constructs composed of layer-specific neurons derived from human pluripotent stem cells. I also completed my PhD at the University of Oxford in 2021, where I investigated neural progenitor polarity and uncovered mechanisms underlying cortical mispositioning in Galectin-3–deficient embryos. Before coming to Oxford, I graduated in Biology at the Universidade Estadual Paulista and completed a Master's degree in the A.C.Camargo Cancer Center in Brazil.
Recent publications
Neuroserpin: A Potential Neuroprotective Agent in Mild Neonatal Hypoxic-Ischaemic Encephalopathy.
Journal article
Kawashita E. et al, (2025), Cells, 14
Galectin-3 induces neurodevelopmental apical-basal polarity and regulates gyrification.
Journal article
Soares LC. et al, (2025), Sci Adv, 11
ATR-hippo drives force signaling to nuclear F-actin and links mechanotransduction to neurological disorders.
Journal article
Chatzifrangkeskou M. et al, (2025), Sci Adv, 11
RSK1 and RSK2 modulate the translatome of glioblastoma cells in an isoform-specific and mTORC1 independent manner.
Journal article
Roffé M. et al, (2025), Neurooncol Adv, 7

