Tanya Singh

I started my career in neuroscience research by working at Pankaj Seth’s lab at the National Brain Research Centre in India, where I learned the reprogramming of blood cells into iPSCs and investigated miRNA-mediated mechanisms governing gene expression in iPSCs. I moved to the UK for my doctoral studies (2017-2021) in Dr. Yasir Syed’s lab at the Neuroscience and Mental Health Innovation Institute (NMHII), Cardiff University. During my PhD, I delved into the iPSC-derived astrocytes and microglia, unraveling their significance in the progression of neuropsychiatric disorders mediated by the 1q21.1 CNV, a domain previously overshadowed by neuronal-centric research. I hold my first post-doctoral tenure (2021-2024) with Prof. Zam Cader at NDCN, University of Oxford where I worked on development of 2D and 3D stem cell models to investigate the molecular mechanism of epileptogenesis in Tuberous Sclerosis Complex. In 2024, I joined DPAG as a Postdoctoral Research Scientist at the Salman and Wade-Martins group, as part of the EU-funded CONNECT Project, where my research focus on elucidating cellular connectivity within the intricate context of neurodegenerative disorders. Embracing an interdisciplinary approach, my goal is to integrate microfluidics and patient-derived stem cells to develop brain organoid models, aiming to shed light on the Parkinson’s disease progression, unlock novel mechanistic insights and identify new therapeutic targets.