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Tanya Singh
Postdoctoral Research Scientist
I am a Postdoctoral Scientist in Salman group, where I work on gut-brain iPSC models. My research aims to uncover how the gut and brain communicate, and how this interaction is shaped by genetic and environmental factors in Parkinson’s disease.
My career in neuroscience research began in Prof. Pankaj Seth’s lab at the National Brain Research Centre (2015-2017) in India, where I learned to reprogram blood cells into iPSCs and studied miRNA-mediated regulation of gene expression in iPSCs. I then moved to the UK for my doctoral studies (2017-2021) in Dr. Yasir Syed’s lab at the Neuroscience and Mental Health Innovation Institute (NMHII), Cardiff University, where I focused on iPSC-derived astrocytes and microglia and their roles in neuropsychiatric disorders associated with the 1q21.1 CNV. I later completed my first postdoctoral position (2021-2024) with Prof. Zam Cader at NDCN, University of Oxford, where I developed 2D and 3D stem cell models to investigate the molecular mechanisms of epileptogenesis in Tuberous Sclerosis Complex.
Recent publications
Human induced pluripotent stem cell-derived microglia with 1q21.1 deletion and duplication exhibit aberrant inflammatory response
Journal article
Singh T. et al, (2026), Genes and Diseases, 13
Modeling the Inflammatory Response of Traumatic Brain Injury Using Human Induced Pluripotent Stem Cell Derived Microglia.
Journal article
Alam A. et al, (2023), J Neurotrauma, 40, 2164 - 2173
Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome.
Journal article
Chapman G. et al, (2022), Mol Psychiatry, 27, 819 - 830
MiRNA-137-mediated modulation of mitochondrial dynamics regulates human neural stem cell fate.
Journal article
Channakkar AS. et al, (2020), Stem Cells, 38, 683 - 697

