Research groups
Colleges
Mathilda Mommersteeg
Associate Professor of Developmental and Regenerative Medicine
I obtained my PhD in 2009 from the University of Amsterdam, where I worked in the laboratories of Prof. Vincent Christoffels and Prof. Antoon Moorman on the development of the conduction system and venous pole of the mammalian heart. In 2010, I joined the laboratory of Prof. John Parnavelas at University College London (UCL) as a long-term EMBO fellow. At UCL, my work focused on deciphering the roles of the Slit-Robo signalling pathway during mammalian heart development. While at UCL, I set up a project researching heart regeneration in Mexican cavefish together with dr. Yoshiyuki Yamamoto, which was sponsored by the British Heart Foundation in 2012. Both my post-doctoral projects form the basis for my current research interests in investigating the molecular mechanisms underlying heart regeneration and development.
Recent publications
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Tissue-Specific Roles for the Slit-Robo Pathway During Heart, Caval Vein, and Diaphragm Development.
Journal article
Zhao J. et al, (2022), J Am Heart Assoc
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Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method
Journal article
Potts HG. et al, (2022), Cells, 11, 608 - 608
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A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution.
Journal article
Warren WC. et al, (2021), Nat Commun, 12
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Unlocking the Secrets of the Regenerating Fish Heart: Comparing Regenerative Models to Shed Light on Successful Regeneration.
Journal article
Potts HG. et al, (2021), J Cardiovasc Dev Dis, 8
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T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system.
Journal article
Mohan RA. et al, (2020), Proc Natl Acad Sci U S A