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Jess Livesey

DPhil Student

I completed my undergraduate studies at Durham University, where I obtained a BSc (Hons) degree in Biological Sciences. I completed a laboratory research project with Dr Paul Chazot, using a motor neuron cell line modelling Amyotrophic lateral sclerosis (ALS) to examine the potential of retinoic acid receptor-targeted drugs as a therapeutic approach for neurodegenerative disease.

In September 2020, I joined the Oxford BBSRC Interdisciplinary Bioscience Doctoral Training Programme. I completed a rotation project in the Becker group, exploring a potential network of genes in the developing cerebellum with roles in language acquisition, before joining the Cragg group.

My DPhil project research aims to define the mechanisms by which neurotransmitters such as noradrenaline regulate the release of dopamine in the striatum, using techniques including fast-scan cyclic voltammetry and genetically-encoded G-protein-coupled-receptor activation-based (GRAB) sensors to monitor neurotransmitter release in real-time.