Jakub Tomek

Within my Sir Henry Wellcome Fellowship, I am researching the role of cardiac diabetic remodeling in arrhythmogenesis and pro-arrhythmic drug interactions. To this end, I combine whole-heart experiments, subcellular imaging, and advanced computational simulations of human cardiomyocytes. The project is hosted within the Zaccolo lab.

I was previously a postdoc in the lab of Prof. Don Bers at UC Davis (investigation of CaMKII function, image processing, computer model development), Prof. Neil Herring at Oxford (experimental investigation of the function of the Neuropeptide Y), and Prof. Blanca Rodriguez (developing computational human electrophysiology models and simulation tools; featured at https://www.dpag.ox.ac.uk/news/new-human-heart-model-set-to-boost-future-cardiac-research-and-therapies). 

I obtained a DPhil from the Department of Physiology, Anatomy, and Genomics at the University of Oxford, where I used a combination of experimental, image processing, and computational modelling approaches to study the role of sympathetic nervous innervation in arrhythmogenesis following myocardial infarction.