Myocardial labile iron handling and its implications following intravenous iron therapy
I spent a year working with the Lakhal-Littleton Group as part of the Final Honour School in Medical Sciences while reading Pre-clinical Medicine at Brasenose College.
We investigated the differential uptake of iron into atrial and ventricular cardiomyocytes, in response to intravenous iron treatment and haemochromatosis, and identified patterns of expression of iron homeostasis genes in the myocardium which could account for these differences.
I will now be reading for an intercalated DPhil to further some of this work before continuing with clinical school. I am interested in ferric carboxymaltose, an intravenous iron therapy increasingly used to support medical therapy in patients with heart failure and other cardiovascular diseases, and its effects on cardiac function.