Christopher Ashley
Emeritus Professor of Physiology
Professor Chris Ashley, after doctoral work at the University of Bristol with Professor Peter Caldwell FRS, spent three years in the US as a Fulbright Travel Scholar, where he developed in 1967 with his colleague Ellis Ridgway, the novel aequorin luminescence method for measuring transient free calcium events in cells, pre-dating by some 10 years the development of calcium-sensitive fluorescent dyes to measure these intracellular phenomena. He returned to Bristol and was appointed to a University Lectureship in Physiology in 1970, and then to Oxford in 1976 as University Lecturer in Physiology and Medical Tutor at Corpus Christi College. He was awarded a DSc from the University of Oxford in 1987, elected an Hon MRCP by the Royal College of Physicians in 1998 and to a Fellowship of the Academy of Medical Sciences in 2002. He is Editor in Chief of the Journal of Muscle Research and Cell Motility, which he co-founded in 1980 with Richard Tregear.
Recent publications
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Professor Andrew Fielding Huxley, OM, FRS, 1917-2012.
Journal article
Ashley CC., (2012), J Muscle Res Cell Motil, 33
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Synchronous in situ ATPase activity, mechanics, and Ca2+ sensitivity of human and porcine myocardium.
Journal article
Griffiths PJ. et al, (2009), Biophys J, 97, 2503 - 2512
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Laser flash photolysis of diazo-2, a caged calcium chelator: The relationship between the extent and rate of smooth muscle relaxation
Journal article
Pelc R. et al, (2009), JOURNAL OF LASER APPLICATIONS, 21, 32 - 38
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DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation.
Journal article
Preston LC. et al, (2007), Biochem Biophys Res Commun, 360, 27 - 32
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Functional effects of the DCM mutant Gly159Asp troponin C in skinned muscle fibres.
Journal article
Preston LC. et al, (2007), Pflugers Arch, 453, 771 - 776