Research groups
Charles Sweeney
B.A. (Mod. Physiology) (Hons)
Research Assistant
I grew up in Ballyfermot, Dublin, in the Republic of Ireland. I am a graduate from Trinity College Dublin's biomedical science program. In the latter half of my degree, I was delighted to read physiology as my moderatorship (B.A. Mod. Physiology Class of 2022). Prior to my work in DPAG, I undertook two undergraduate research projects in the area of neurophysiology. I'm proficient in a variety of experimental techniques, from iPSC stem cell culture to electrophysiology. I am fascinated with the mechanisms underpinning health and disease at sites where multiple organ systems intersect.
As a research assistant, I'm a member of a vibrant research group in DPAG, investigating the neurobiological basis of obesity, focusing on the role of sympathetic neural networks. In April 2023, I began working in the Department of Physiology, Anatomy & Genetics at the University of Oxford as a full-time, on-site member of research support staff. I provided technical, research, and administrative support to ensure the smooth running of Domingo's laboratory. During my onsite work, I significantly contributed to a number of primary research articles currently in preparation.
From September 2024, I began working part-time and remotely for the Domingos group, focusing on administrative support, academic writing and data analysis. The same month, I also began my studies as a graduate entry medicine student at University College Dublin.
Recent publications
Neuroimmunometabolism in Health and Disease.
Journal article
Sweeney CAP. et al, (2026), Annu Rev Immunol
Class A Scavenger Receptor MARCO negatively regulates Ace expression and aldosterone production.
Preprint
O'Brien CJO. et al, (2025)
Neuroimmunometabolism as a regulator of obesity
Chapter
Sweeney CAP. and Domingos AI., (2025), 227 - 262
MARCO in alveolar macrophages negatively regulates Ace expression and aldosterone production
Preprint
O’Brien CJO. et al, (2023)
Distinct adrenal gland macrophages regulate corticosteroid production
Preprint
O’Brien CJO. et al, (2023)

