Cecilia Velasco Dominguez
Contact information
Research groups
Cecilia Velasco Dominguez
Dr. Cecilia Velasco completed her PhD in 2022 under Prof. Artur Llobet at the University of Barcelona where she studied the neurobiology of the presynaptic terminal using autaptic cultures. She described a mechanism of presynaptic homeostatic plasticity in response to synapse elimination and demonstrated that presynaptic microtubule dynamics contributes to spontaneous synaptic vesicle release.
She later joined the laboratory of Prof. Gero Miesenböck where she is currently a postdoctoral researcher at the University of Oxford (DPAG, Center of Neural Circuits and Behaviour). Her project aims to investigate the changes in synaptic activity that promote sleep in the fruit fly by combining electrophysiology with genetics, optogenetics and transcriptomics. The ultimate goal of her project is to advance our understanding in the molecular mechanisms underlying homeostatic sleep regulation.
IN 2025 Cecilia received a Wellcome Early-Career Award
Recent publications
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Mitochondrial origins of the pressure to sleep.
Journal article
Sarnataro R. et al, (2025), Nature
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NEAT1-mediated regulation of proteostasis and mRNA localization impacts autophagy dysregulation in Rett syndrome
Journal article
Siqueira E. et al, (2025), Nucleic Acids Research, 53
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Protocol to correlate electron microscopy with electrophysiology in single-cell autaptic microcultures
Journal article
Martínez San Segundo P. et al, (2024), STAR Protocols, 5, 103003 - 103003
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Mitochondrial origins of the pressure to sleep
Preprint
Sarnataro R. et al, (2024)
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Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro
Journal article
Velasco CD. et al, (2023), Communications Biology, 6

