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Research groups

DPAG News

Jeff David AnaAna Domingos reflects on past experiences working with DPAG's inaugural Hans Krebs Lecture speaker, Jeffrey Friedman, who has been awarded the Breakthrough Prize in Life Sciences. Read more here.

Ana Domingos

Associate Professor of Neuroscience

  • Tutor of Medicine at Lady Margaret Hall

The Domingos laboratory researches neuroimmune mechanisms underlying obesity. They discovered the sympathetic neuro-adipose junction, a functional synapse-like connection between white adipocytes and the sympathetic nervous system (Cell 2015). They found that this neuro-adipose junction is necessary and sufficient for fat mass reduction via norepinephrine (NE) signaling (Cell 2015, Nature Comm 2017). They then discovered Sympathetic neuron-Associated Macrophages (SAMs) that directly import and metabolize NE. Abrogation of SAM function promotes long-term amelioration of obesity independently of food intake (Nature Medicine, 2017).

About Ana's Work on Obesity

© Lady Margaret Hall / Dominik Osvald / www.dominikosvald.com

Optogenetics in NeuroImmunity

UPCOMING CONFERENCES

EMBO Workshop, Organ crosstalk in energy balance and metabolic diseaseSancti Petri, Chiclana, Cádiz, Spain,  April 8-11 2019

Aegean Conferences, 4th International Conference on ImmunoMetabolism: Molecular and Cellular Immunology of Metabolism, Rhodes, Greece May 28  - June 2 2019

ICMS, 14th World Congress on Inflammation, Sydney, September 15-19 2019

Cell Symposia, Neuro-Immune Axis: Reciprocal Regulation in Development, Health and Disease, Long Beach, California, September 22-24 2019

Nature Conferences, Advances in Metabolic CommunicationRio de Janeiro, Brazil, October 15 - 18 2019

Key publications