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Research groups

Alexander Demby

BA (Oxon)

MB DPhil Student

I am studying a combined programme, integrating a BM BCh in Clinical Medicine with a DPhil in Physiology, Anatomy and Genetics. 

I am now in the third year of my DPhil, working in the Zaccolo Group. My research focuses on signal transduction by G protein-coupled receptors (GPCRs). It is now well established that GPCRs achieve response specificity through compartmentalisation of intracellular signals. My project investigates how receptors coordinate this compartmentalisation in cardiac myocytes with a particular focus on the cAMP/PKA signalling pathway.