Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

If you have a question about this talk, please contact Sarah Noujaim.


Subplate neurons have an essential role in cortical circuit formation. They are amongst the earliest formed neurons of the cerebral cortex, are located at the junction of white and grey matter and necessary for correct thalamocortical axon ingrowth. Recent transcriptomic characterizations provide opportunities for monitoring and modulating selected subpopulations of these cells. Mouse lines expressing reporter genes have demonstrated novel, extra-cortical subplate neurogenesis and shown how subplate cells are integrated under the influence of sensory activity into cortical and extracortical circuits.