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Cortical Microcircuitry in Behaviour

The goal of the Bruno Lab's research is to understand the neural networks that produce sensory behaviours: how the various layers of the neocortex and thalamic nuclei contribute to sensory perception of the environment, learning, and decision making. Our experiments combine sensory behaviours with intracellular physiology, array recordings, two-photon microscopy, optogenetics, and computational modelling. We focus on the whisker-barrel system, which is one of the main means by which rodents explore their environments. Please visit our new research group web page 

Brains of Human and Mouse© Rikki Rabinovich, Bruno Lab

Our team

Selected publications

Effects of arousal and movement on secondary somatosensory and visual thalamus.

Journal article

Petty GH. et al, (2021), Elife, 10

man-specific modifier of cortical connectivity and circuit function.

Journal article

Schmidt ERE. et al, (2021), Nature, 599, 640 - 644

Sensorimotor strategies and neuronal representations for shape discrimination.

Journal article

Rodgers CC. et al, (2021), Neuron, 109, 2308 - 2325.e10

Reinforcement Learning Recruits Somata and Apical Dendrites across Layers of Primary Sensory Cortex.

Journal article

Lacefield CO. et al, (2019), Cell Rep, 26, 2000 - 2008.e2

Sensation, movement and learning in the absence of barrel cortex.

Journal article

Hong YK. et al, (2018), Nature, 561, 542 - 546

Related research themes

We host a number of internationally recognised neuroscience groups, with expertise in a wide range of experimental and computational methods.
Neuroscience

We host a number of internationally recognised ...