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Publications

Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD.

Guiraud S. et al, (2019), Hum Mol Genet, 28, 307 - 319

Micro-utrophin Improves Cardiac and Skeletal Muscle Function of Severely Affected D2/mdx Mice.

Kennedy TL. et al, (2018), Mol Ther Methods Clin Dev, 11, 92 - 105

Invited comment to: European Hernia Society guidelines on prevention and treatment of parastomal hernias.

Osborne W. et al, (2018), Hernia, 22, 207 - 208

Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.

Kennedy TL. et al, (2017), Skelet Muscle, 7

Identification of serum protein biomarkers for utrophin based DMD therapy.

Guiraud S. et al, (2017), Sci Rep, 7

Second-generation compound for the modulation of utrophin in the therapy of DMD.

Guiraud S. et al, (2015), Hum Mol Genet, 24, 4212 - 4224

New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD)

Fairclough RJ. et al, (2014), NEUROMUSCULAR DISORDERS, 24, 821 - 821

Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy

Fairclough RJ. et al, (2012), NEUROMUSCULAR DISORDERS, 22, S3 - S3

Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression

Ravenscroft G. et al, (2011), PLoS ONE, 6

Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.

Tinsley JM. et al, (2011), PLoS One, 6

Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression.

Ravenscroft G. et al, (2011), PLoS One, 6

Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.

Nowak KJ. et al, (2009), J Cell Biol, 185, 903 - 915

Prevention of pathology in mdx mice by expression of utrophin: analysis using an inducible transgenic expression system.

Squire S. et al, (2002), Hum Mol Genet, 11, 3333 - 3344

Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.

Fisher R. et al, (2001), Neuromuscul Disord, 11, 713 - 721

Analysis of mutations in Survival of Motor Neuron (SMN1) gene through model systems.

Owen N. et al, (2001), AMERICAN JOURNAL OF HUMAN GENETICS, 69, 368 - 368

Non-toxic ubiquitous overexpression of utrophin in the mdx mouse.

Fisher R. et al, (2000), AMERICAN JOURNAL OF HUMAN GENETICS, 67, 428 - 428

Dystrophin and utrophin influence fiber type composition and post-synaptic membrane structure.

Rafael JA. et al, (2000), Hum Mol Genet, 9, 1357 - 1367

Include forthcoming?