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Publications

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation.

Do QB. et al, (2024), NPJ Parkinsons Dis, 10

Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease.

Kilfeather P. et al, (2024), Cell Rep, 43

Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models.

Williamson MG. et al, (2023), Hum Mol Genet, 32, 2808 - 2821

Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons.

Beccano-Kelly DA. et al, (2023), iScience, 26

Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson's disease GBA-N370S dopamine neurons.

Bogetofte H. et al, (2023), Cell Rep, 42

Tau-dependent HDAC1 nuclear reduction is associated with altered VGluT1 expression.

Siano G. et al, (2023), Front Cell Dev Biol, 11

Gene Expression of Disease-related Genes in Alzheimer's Disease is Impaired by Tau Aggregation.

Siano G. et al, (2020), J Mol Biol, 432

What we can learn from iPSC-derived cellular models of Parkinson's disease.

Caiazza MC. et al, (2020), 252, 3 - 25

Modulation of Tau Subcellular Localization as a Tool to Investigate the Expression of Disease-related Genes

Siano G. et al, (2019), Journal of Visualized Experiments

Identification of an ERK Inhibitor as a Therapeutic Drug Against Tau Aggregation in a New Cell-Based Assay

Siano G. et al, (2019), Frontiers in Cellular Neuroscience, 13

Tau Modulates VGluT1 Expression

Siano G. et al, (2019), Journal of Molecular Biology, 431, 873 - 884

Include forthcoming?