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Publications

Compartmentalized cAMP signalling and control of cardiac rhythm.

Tomek J. and Zaccolo M., (2023), Philos Trans R Soc Lond B Biol Sci, 378

Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.

Subramaniam G. et al, (2023), Circ Res

Regulation of cardiac function by cAMP nanodomains.

Folkmanaite M. and Zaccolo M., (2023), Biosci Rep

Compartmentalised cAMP signalling in the primary cilium.

Paolocci E. and Zaccolo M., (2023), Front Physiol, 14

Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation

Park KC. et al, (2023), Nature Cardiovascular Research

Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains.

Ren L. et al, (2022), JCI Insight, 7

Abnormal Cyclic Nucleotide Signaling at the Outer Mitochondrial Membrane In Sympathetic Neurons During the Early Stages of Hypertension.

Li D. et al, (2022), Hypertension

Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.

Anton SE. et al, (2022), Cell

Deciphering cellular signals in adult mouse sinoatrial node cells.

Reddy GR. et al, (2022), iScience, 25

Inhibition of adenylyl cyclase 1 by ST034307 inhibits IP3-evoked changes in sino-atrial node beat rate.

Bose SJ. et al, (2022), Front Pharmacol, 13

Micro-2D Cell Culture for cAMP Measurements Using FRET Reporters in Human iPSC-Derived Cardiomyocytes.

Koschinski A. and Zaccolo M., (2022), Methods Mol Biol, 2483, 141 - 165

Preface

Zaccolo M., (2022), 2483, v - vi

Quantitative Phosphoproteomics to Study cAMP Signaling

Schleicher K. et al, (2022), Methods in molecular biology (Clifton, N.J.), 2483, 281 - 296

CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors.

Manfra O. et al, (2021), Cardiovasc Res

Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.

Simon JN. et al, (2021), Circulation, 143, 449 - 465

AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels.

Kar P. et al, (2021), Function (Oxf), 2

cAMP Buffering via Liquid-Liquid Phase Separation.

Zaccolo M., (2021), Function (Oxf), 2

In Silico Human Induced Pluripotent Stem Cell Derived Cardiomyocyte Electro-Mechanical Modelling and Simulation

Folkmanaite M. et al, (2021), Computing in Cardiology, 2021-September

IP3-mediated Ca2+ release regulates atrial Ca2+ transients and pacemaker function by stimulation of adenylyl cyclases.

Capel RA. et al, (2021), Am J Physiol Heart Circ Physiol, 320, H95 - H107

Subcellular Organization of the cAMP Signaling Pathway.

Zaccolo M. et al, (2021), Pharmacol Rev, 73, 278 - 309

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