GPCR signalling: Yet another variant route in a highly complex road map.
Demby A. and Zaccolo M., (2024), Cell Calcium, 124
Nanodomain cAMP signalling in cardiac pathophysiology: potential for developing targeted therapeutic interventions.
Zaccolo M. and Kovanich D., (2024), Physiol Rev
Phase separation of protein kinase A: a new paradigm in cardiac regulation?
Folkmanaite M. and Zaccolo M., (2024), Nat Rev Cardiol
Compartmentalized cAMP signalling and control of cardiac rhythm.
Tomek J. and Zaccolo M., (2023), Philos Trans R Soc Lond B Biol Sci, 378
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.
Subramaniam G. et al, (2023), Circ Res
Regulation of cardiac function by cAMP nanodomains.
Folkmanaite M. and Zaccolo M., (2023), Biosci Rep
Compartmentalised cAMP signalling in the primary cilium.
Paolocci E. and Zaccolo M., (2023), Front Physiol, 14
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation
Park KC. et al, (2023), Nature Cardiovascular Research
Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains.
Ren L. et al, (2022), JCI Insight, 7
Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.
Anton SE. et al, (2022), Cell
Deciphering cellular signals in adult mouse sinoatrial node cells.
Reddy GR. et al, (2022), iScience, 25
Inhibition of adenylyl cyclase 1 by ST034307 inhibits IP3-evoked changes in sino-atrial node beat rate.
Bose SJ. et al, (2022), Front Pharmacol, 13
Micro-2D Cell Culture for cAMP Measurements Using FRET Reporters in Human iPSC-Derived Cardiomyocytes.
Koschinski A. and Zaccolo M., (2022), Methods Mol Biol, 2483, 141 - 165
Quantitative Phosphoproteomics to Study cAMP Signaling
Schleicher K. et al, (2022), Methods in molecular biology (Clifton, N.J.), 2483, 281 - 296
CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors.
Manfra O. et al, (2021), Cardiovasc Res
Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.
Simon JN. et al, (2021), Circulation, 143, 449 - 465
AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels.
Kar P. et al, (2021), Function (Oxf), 2