MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo.
Fiedler LR. et al, (2019), Cell Stem Cell, 24, 579 - 591.e12
Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo
Zhou J. et al, (2019), Human Molecular Genetics
Inhibiting the Inhibitors, PTP1B as a Therapeutic Target in Myocardial Infarction
Fiedler LR., (2018), Heart Research - Open Journal, 5, 8 - 11
Titin-truncating variants affect heart function in disease cohorts and the general population
Schafer S. et al, (2016), Nature Genetics, 49, 46 - 53
APPROACHES FOR PHARMACOLOGICAL INHIBITION OF CARDIAC CELL DEATH: MAP4K4 AS A THERAPEUTIC TARGET
Fiedler L. et al, (2014), HEART, 100, A91 - A91
T₁ mapping detects pharmacological retardation of diffuse cardiac fibrosis in mouse pressure-overload hypertrophy.
Stuckey DJ. et al, (2014), Circ Cardiovasc Imaging, 7, 240 - 249
Mouse models of heart failure: cell signaling and cell survival.
Fiedler LR. et al, (2014), Curr Top Dev Biol, 109, 171 - 247
The ADMA/DDAH pathway regulates VEGF-mediated angiogenesis.
Fiedler LR. et al, (2009), Arterioscler Thromb Vasc Biol, 29, 2117 - 2124
The DDAH/ADMA pathway in the control of endothelial cell migration and angiogenesis.
Fiedler LR. and Wojciak-Stothard B., (2009), Biochem Soc Trans, 37, 1243 - 1247
Rac1 regulates cardiovascular development and postnatal function of endothelium.
Fiedler LR., (2009), Cell Adh Migr, 3, 143 - 145
Decorin regulates endothelial cell-matrix interactions during angiogenesis.
Fiedler LR. and Eble JA., (2009), Cell Adh Migr, 3, 3 - 6
The DDAH/ADMA pathway is a critical regulator of NO signalling in vascular homeostasis.
Fiedler L., (2008), Cell Adh Migr, 2, 149 - 150
Decorin regulates endothelial cell motility on collagen I through activation of insulin-like growth factor I receptor and modulation of alpha2beta1 integrin activity.
Fiedler LR. et al, (2008), J Biol Chem, 283, 17406 - 17415
Breaking Female Hearts: The Gender Gap in Cardiovascular Research
Fiedler LR., Heart Research - Open Journal, 3, e1 - e5
Cardiovascular Research: Past, Present and Future
Fiedler LR., Heart Research - Open Journal, 2, 70 - 81
Pharmacological Agents in the Clinic: Trial and Error
Fiedler LR., Heart Research - Open Journal, 2, 126 - 130