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Publications

Compartmentalisation proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation

PLATT F., (2024), iScience

Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of its Pathology.

Heather LC. et al, (2024), Diabetes

CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease.

Glatz JFC. et al, (2023), Physiol Rev

Targeting mitochondrial oxidative phosphorylation: lessons, advantages, and opportunities.

Machado ND. et al, (2023), Br J Cancer, 129, 897 - 899

Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia-reperfusion injury.

Chu SM. et al, (2023), Exp Physiol, 108, 874 - 890

Post-translational palmitoylation of metabolic proteins.

Dennis KMJH. and Heather LC., (2023), Front Physiol, 14

Cardiometabolic risk factors vary with age differently in females and males

Miller JJ. and Heather LC., (2022), Nature Cardiovascular Research, 1, 796 - 797

Unravelling the role of acidic organelles in Goat Atrial Fibrillation

Ayagama T. et al, (2022), ACTA PHYSIOLOGICA, 236, 931 - 933

Guidelines on Models of Diabetic Heart Disease.

Heather LC. et al, (2022), Am J Physiol Heart Circ Physiol

Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents.

Hazlehurst JM. et al, (2022), Metabol Open, 14

Deletion of tetrahydrobiopterin synthesis in cardiomyocytes causes downregulation of fatty acid metabolism whilst protected against cardiac ischemia reperfusion injury

Chu S. et al, (2022), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 173, S125 - S125

Human metabolism: pathways and clinical aspects

Evans RD. and Heather LC., (2022), Surgery (United Kingdom)

Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart.

da Luz Sousa Fialho M. et al, (2021), Diabetes

Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischemia.

Kerr M. et al, (2021), FASEB J, 35

Rapid, B 1 -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.

Miller JJ. et al, (2021), Magn Reson Med, 85, 2978 - 2991

Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes.

Lopez CA. et al, (2021), Sci Rep, 11

Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.

Savic D. et al, (2021), NMR Biomed, 34

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI.

Savic D. et al, (2021), Metabolites, 11

Peritransplant Cardiometabolic and Mitochondrial Function: The Missing Piece in Donor Heart Dysfunction and Graft Failure.

Wells MA. et al, (2021), Transplantation, 105, 496 - 508

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.

Timm KN. et al, (2020), Commun Biol, 3

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