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Publications

Cancer Therapy-Induced Cardiotoxicity—A Metabolic Perspective on Pathogenesis, Diagnosis and Therapy

Choksey A. and Timm KN., (2021), International Journal of Molecular Sciences, 23, 441 - 441

Rapid, B 1 -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.

Miller JJ. et al, (2021), Magn Reson Med, 85, 2978 - 2991

Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.

Savic D. et al, (2021), NMR Biomed, 34

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI.

Savic D. et al, (2021), Metabolites, 11

A 3D hybrid-shot spiral sequence for hyperpolarized 13 C imaging.

Tyler A. et al, (2021), Magn Reson Med, 85, 790 - 801

Metabolic Effects of Doxorubicin on the Rat Liver Assessed With Hyperpolarized MRI and Metabolomics.

Timm KN. et al, (2021), Front Physiol, 12

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.

Timm KN. et al, (2020), Commun Biol, 3

Nicotinic acid receptor agonists impair myocardial contractility by energy starvation.

Watson WD. et al, (2020), FASEB J, 34, 14878 - 14891

Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR.

Marco-Rius I. et al, (2020), MAGMA

A 3D hybrid-shot spiral sequence for hyperpolarized 13C imaging

TYLER D. et al, (2020), Magnetic Resonance in Medicine

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol.

Kerr M. et al, (2020), JCI Insight, 5

The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity.

Timm KN. and Tyler DJ., (2020), Cardiovasc Drugs Ther, 34, 255 - 269

Novel dietary ketone ester lowers fasting blood glucose levels in Zucker diabetic fatty rats

Chong CR. et al, (2020), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 140, 26 - 27

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS.

Timm KN. et al, (2018), NMR Biomed, 31

Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes.

Dodd MS. et al, (2018), JACC Basic Transl Sci, 3, 485 - 498

Investigating real-time metabolic flux changes in a rat model of doxorubicin-induced cardiotoxicity using hyperpolarized 13C magnetic resonance spectroscopy

Timm KN. et al, (2018), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 120, 34 - 34

Cardiac applications of hyperpolarised magnetic resonance.

Timm KN. et al, (2018), Prog Nucl Magn Reson Spectrosc, 106-107, 66 - 87

DEPLETION OF CARDIAC SUCCINATE MEDIATES IMPAIRED HYPOXIA-INDUCIBLE FACTOR 1A SIGNALLING BY LONG CHAIN FATTY ACIDS IN INSULIN RESISTANCE

Dodd MS. et al, (2018), HEART, 104, A11 - A11

EFFECTS OF CARNITINE SUPPLEMENTATION IN THE TYPE 1 DIABETIC HEART: AN IN VIVO HYPERPOLARIZED MRS STUDY

Savic D. et al, (2018), HEART, 104, A12 - A12

HYPERPOLARIZED 13C MAGNETIC RESONANCE SPECTROSCOPY IDENTIFIES CHANGES TO MYOCARDIAL METABOLIC FLUXES IN A RAT MODEL OF DOXORUBICIN-INDUCED CARDIOTOXICITY

Timm KN. et al, (2018), HEART, 104, A7 - A8

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