Cancer Therapy-Induced Cardiotoxicity—A Metabolic Perspective on Pathogenesis, Diagnosis and Therapy
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Choksey A. and Timm KN., (2021), International Journal of Molecular Sciences, 23, 441 - 441
Rapid, B 1 -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.
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Miller JJ. et al, (2021), Magn Reson Med, 85, 2978 - 2991
Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.
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Savic D. et al, (2021), NMR Biomed, 34
L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI.
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Savic D. et al, (2021), Metabolites, 11
A 3D hybrid-shot spiral sequence for hyperpolarized 13 C imaging.
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Tyler A. et al, (2021), Magn Reson Med, 85, 790 - 801
Metabolic Effects of Doxorubicin on the Rat Liver Assessed With Hyperpolarized MRI and Metabolomics.
Journal article
Timm KN. et al, (2021), Front Physiol, 12
Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.
Journal article
Timm KN. et al, (2020), Commun Biol, 3
Nicotinic acid receptor agonists impair myocardial contractility by energy starvation.
Journal article
Watson WD. et al, (2020), FASEB J, 34, 14878 - 14891
Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR.
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Marco-Rius I. et al, (2020), MAGMA
A 3D hybrid-shot spiral sequence for hyperpolarized 13C imaging
Journal article
TYLER D. et al, (2020), Magnetic Resonance in Medicine
Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol.
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Kerr M. et al, (2020), JCI Insight, 5
The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity.
Journal article
Timm KN. and Tyler DJ., (2020), Cardiovasc Drugs Ther, 34, 255 - 269
Novel dietary ketone ester lowers fasting blood glucose levels in Zucker diabetic fatty rats
Conference paper
Chong CR. et al, (2020), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 140, 26 - 27
Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS.
Journal article
Timm KN. et al, (2018), NMR Biomed, 31
Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes.
Journal article
Dodd MS. et al, (2018), JACC Basic Transl Sci, 3, 485 - 498
Investigating real-time metabolic flux changes in a rat model of doxorubicin-induced cardiotoxicity using hyperpolarized 13C magnetic resonance spectroscopy
Conference paper
Timm KN. et al, (2018), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 120, 34 - 34
Cardiac applications of hyperpolarised magnetic resonance.
Journal article
Timm KN. et al, (2018), Prog Nucl Magn Reson Spectrosc, 106-107, 66 - 87
DEPLETION OF CARDIAC SUCCINATE MEDIATES IMPAIRED HYPOXIA-INDUCIBLE FACTOR 1A SIGNALLING BY LONG CHAIN FATTY ACIDS IN INSULIN RESISTANCE
Conference paper
Dodd MS. et al, (2018), HEART, 104, A11 - A11
EFFECTS OF CARNITINE SUPPLEMENTATION IN THE TYPE 1 DIABETIC HEART: AN IN VIVO HYPERPOLARIZED MRS STUDY
Conference paper
Savic D. et al, (2018), HEART, 104, A12 - A12
HYPERPOLARIZED 13C MAGNETIC RESONANCE SPECTROSCOPY IDENTIFIES CHANGES TO MYOCARDIAL METABOLIC FLUXES IN A RAT MODEL OF DOXORUBICIN-INDUCED CARDIOTOXICITY
Conference paper
Timm KN. et al, (2018), HEART, 104, A7 - A8