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Publications

Competitive Interactions between Halothane and Isoflurane at the Carotid Body and TASK Channels.

Pandit JJ. et al, (2020), Anesthesiology, 133, 1046 - 1059

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control.

Cheng X. et al, (2020), J Clin Invest, 130, 2237 - 2251

Influence of propofol on isolated neonatal rat carotid body glomus cell response to hypoxia and hypercapnia.

O'Donohoe PB. et al, (2019), Respir Physiol Neurobiol, 260, 17 - 27

A1899, PK-THPP, ML365, and Doxapram inhibit endogenous TASK channels and excite calcium signaling in carotid body type-1 cells.

O'Donohoe PB. et al, (2018), Physiol Rep, 6

PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies.

Fielding JW. et al, (2018), J Physiol

RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity.

Bardsley EN. et al, (2018), Sci Rep, 8

Neurotransmitter Switching Coupled to β-Adrenergic Signaling in Sympathetic Neurons in Prehypertensive States.

Bardsley EN. et al, (2018), Hypertension, 71, 1226 - 1238

Identification of Novel mRNA Transcripts in the Sympathetic Stellate Ganglia using RNA Sequencing

Bardsley EN. et al, (2018), FASEB JOURNAL, 32

Neurotransmitter Switching in Sympathetic Neurons Coupled to Beta-Adrenergic Signalling in Hypertensive States

Bardsley EN. et al, (2018), FASEB JOURNAL, 32

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.

Hodson EJ. et al, (2016), J Physiol, 594, 1179 - 1195

A method for continuous and stable perfusion of tissue and single cell preparations with accurate concentrations of volatile anaesthetics.

Huskens N. et al, (2016), J Neurosci Methods, 258, 87 - 93

Moderate inhibition of mitochondrial function augments carotid body hypoxic sensitivity.

Holmes AP. et al, (2016), Pflugers Arch, 468, 143 - 155

TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing.

Buckler KJ., (2015), Pflugers Arch, 467, 1013 - 1025

TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing

Buckler KJ., (2015), Pflugers Archiv European Journal of Physiology, 467, 1013 - 1025

Functional Properties of Mitochondria in the Type-1 Cell and Their Role in Oxygen Sensing.

Buckler KJ. and Turner PJ., (2015), 860, 69 - 80

Glycogen metabolism protects against metabolic insult to preserve carotid body function during glucose deprivation.

Holmes AP. et al, (2014), J Physiol, 592, 4493 - 4506

The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia.

Slingo ME. et al, (2014), J Appl Physiol (1985), 116, 885 - 892

Cytosolic calcium regulation in rat afferent vagal neurons during anoxia.

Henrich M. and Buckler KJ., (2013), Cell Calcium, 54, 416 - 427

Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells

Turner PJ. and Buckler KJ., (2013), Journal of Physiology, 591, 5977 - 5998

Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells.

Turner PJ. and Buckler KJ., (2013), J Physiol, 591, 5977 - 5998

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