TRPC3 signalling contributes to the biogenesis of extracellular vesicles
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PTCH1-mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis.
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Moonwalker Mouse
Chapter
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Purkinje Cell Patterning-Insights from Single-Cell Sequencing.
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Apsley EJ. and Becker EBE., (2022), Cells, 11
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Chapter
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MODELLING SHH-MEDULLOBLASTOMA USING CEREBELLAR ORGANOIDS
Conference paper
van Essen M. et al, (2022), NEURO-ONCOLOGY, 24, 2 - 2
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Moonwalker Mouse
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Becker EBE., (2021), Handbook of the Cerebellum and Cerebellar Disorders: Second Edition: Volume 3, 1773 - 1788
Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology.
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Journal article
Van Essen M. et al, (2020), PLoS Genetics
Deconstructing cerebellar development cell by cell.
Journal article
van Essen MJ. et al, (2020), PLoS Genet, 16
TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells.
Journal article
Wu B. et al, (2019), Elife, 8
A gene expression signature in developing Purkinje cells predicts autism and intellectual disability co-morbidity status.
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Clifford H. et al, (2019), Sci Rep, 9
TRPC3 is essential for functional heterogeneity of cerebellar Purkinje cells
Preprint
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Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation.
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Journal article
Watson LM. et al, (2018), Cerebellum, 17, 419 - 427