Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The relative simplicity of the central nervous systems of invertebrates has enabled neurobiologists to study the development of identified neurons in great detail. The insights that these studies have provided are now being applied to the developing vertebrate brain. Both invertebrates and vertebrates follow a similar scheme during early nervous system development, in which a few orthogonally arranged axon tracts establish a simple scaffold in the neuroepithelium. These tracts are then used by projection axons as routes or highways through the developing brain. In the vertebrate brain one of these highways, the tract of the post-optic commissure (tPOC), has been the focus of recent studies. This article describes how the retinofugal projection utilises the scaffold provided by the tPOC. © 1992.

Original publication




Journal article


Seminars in Neuroscience

Publication Date





357 - 363