Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

© 2016 The Czech Society of Cardiology. During the last 10 years, 844 operations of 805 adults with congenital heart disease (CHD) were performed in Hospital Na Homolce in Prague, Czech Republic. The median age was 37 (interquartile range 25-49, full range 16-81) years. Operations of complex and rare CHD represented 47%. Forty-four percent of patients (354) underwent previous cardiac surgery in childhood or adulthood. Three and more operations were performed in 14% (113 patients). Combined surgical procedures were performed in 70% of operations. Thirty-day mortality was 1.36%, hospital mortality 1.7% and 5-year survival probability 97%. The risk factors for early and late mortality were NYHA class III and IV symptoms (p < 0.0001; OR 30.8), history of heart failure (p = 0.001; OR 6.7), cyanosis (p < 0.0001; OR 60.5), number of previous operations (p = 0.00033), presence of mechanical prosthetic valves (p = 0.0032; OR 3.7) and univentricular circulation (p = 0.0276; OR 5.4). The difference was not significant for arrhythmias (p = 0.078), pulmonary hypertension (p = 0.072), age at operation (p = 0.372) and gender (p = 0.48). Centralization of adult CHD care in a high volume center carries very good surgical results with low early and late mortality. It is important to perform the operations in time and to eliminate all residual lesions by combined surgical procedure. The presence of pediatric cardiac surgeon is necessary for the operations of complex CHD.

Original publication




Journal article


Cor et Vasa

Publication Date





e317 - e327