The 31P-nuclear magnetic resonance spectrum of heart: will it be of diagnostic use in clinical cardiology?
Willis RJ., Clarke K.
Significant progress in two areas will be required before the application of magnetic resonance spectroscopy in clinical cardiology is realized. On the technical side, methods must be developed to allow NMR spectra to be obtained non-invasively from the heart uncontaminated by surrounding tissue and with sufficient spatial resolution and signal to noise to be of practical use. On the application side, the potential value of the information derived from the NMR spectrum to diagnosis must be demonstrated. This review addresses the latter problem by evaluating the information content of the 31P-spectrum of heart within the framework of the practical constraints imposed by its possible clinical application as opposed to its acknowledged research application.